Tetrazine-NHS Ester
- CAS No.
- 1616668-55-3
- Chemical Name:
- Tetrazine-NHS Ester
- Synonyms
- Tetrazine-NHS Ester;Tetrazine-Ph-NHS ester;Tetrazine-NHS Ester (CCT-1127);3-(4-phenylacetic acid)-1,2,4,5-tetrazine succinimidyl ester;2,5-Dioxo-1-pyrrolidinyl 4-(1,2,4,5-tetrazin-3-yl)benzeneacetate;2,5-Dioxopyrrolidin-1-yl 2-(4-(1,2,4,5-tetrazin-3-yl)phenyl)acetate;Benzeneacetic acid, 4-(1,2,4,5-tetrazin-3-yl)-, 2,5-dioxo-1-pyrrolidinyl ester
- CBNumber:
- CB93345123
- Molecular Formula:
- C14H11N5O4
- Molecular Weight:
- 313.27
- MDL Number:
- MFCD29052194
- MOL File:
- 1616668-55-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Tetrazine-NHS ester | 901989 | 25MG | $346 |
| Tetrazine-NHS Ester | T4125 | 10MG | $114 |
| Tetrazine-NHS ester | RPC66855 | 25mg | $378 |
| Tetrazine-NHS ester | RPC66855 | 50mg | $529.5 |
| Tetrazine-NHS ester | RPC66855 | 100mg | $756 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
Tetrazine-NHS Ester price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 901989 | Tetrazine-NHS ester | 1616668-55-3 | 25MG | $346 | 2023-01-07 | Buy |
| TCI Chemical | T4125 | Tetrazine-NHS Ester | 1616668-55-3 | 10MG | $114 | 2026-04-30 | Buy |
| Biosynth | RPC66855 | Tetrazine-NHS ester | 1616668-55-3 | 25mg | $378 | 2026-06-05 | Buy |
| Biosynth | RPC66855 | Tetrazine-NHS ester | 1616668-55-3 | 50mg | $529.5 | 2026-06-05 | Buy |
| Biosynth | RPC66855 | Tetrazine-NHS ester | 1616668-55-3 | 100mg | $756 | 2026-06-05 | Buy |
Tetrazine-NHS Ester Chemical Properties,Uses,Production
Description
Tetrazine-NHS Ester is a NHS activated tetrazine linker. NHS ester is very reactive with amine containing molecule. Methyltetrazine enable fast click reaction with TCO (trans-cycloctene).
Uses
Tetrazine-Ph-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Tetrazine-Ph-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
IC 50
Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Tetrazine-NHS Ester Preparation Products And Raw materials
Raw materials
Preparation Products
Tetrazine-NHS Ester Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32467 | 58 |
| Alfa Chemistry | +1-5166625404; | Info@alfa-chemistry.com | United States | 20405 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 | 1924344760@confluore.cn | China | 2997 | 58 |
| Bide Pharmatech Ltd. | 400-400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai Xingui Biotechnology Co., Ltd. | 15121041756 | xingui2022@126.com | China | 9939 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51395 | 80 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847 13636370518 | shyysw007@163.com | China | 89686 | 60 |
| Jinan elephant international trading co., LTD | 13006575422@163.com | China | 6355 | 58 | |
| Aikon International Limited | 025-58859352 15955137747 | sales01@aikonchem.com | China | 16027 | 58 |
View Lastest Price from Tetrazine-NHS Ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-06-07 | Tetrazine NHS ester
1616668-55-3
|
25mg | >99.00% | 100mg | Xian confluore Biological Technology Co., Ltd. |
-
- Tetrazine NHS ester
1616668-55-3
- $0.00
- >99.00%
- Xian confluore Biological Technology Co., Ltd.
