ETHYL-ALPHA-CYANO-4-HYDROXYCINNAMATE
- CAS No.
- 6935-44-0
- Chemical Name:
- ETHYL-ALPHA-CYANO-4-HYDROXYCINNAMATE
- Synonyms
- AKOS UB-20070;RARECHEM AK ML 0354;ETHYL-α-CYANO-4-HYDROXYCINNAMATE;-Ethyl 2-cyano-3-(4-hydroxyphenyl);ETHYL-ALPHA-CYANO-4-HYDROXYCINNAMATE;3-Piperazinecarboxamide,N,N-dimethyl-;ETHYL 2-CYANO-3-(4-HYDROXYPHENYL)ACRYLATE;(E)-Ethyl 2-cyano-3-(4-hydroxyphenyl)acrylate;ethyl (E)-2-cyano-3-(4-hydroxyphenyl)acrylate;methyl (E)-2-cyano-3-(4-hydroxyphenyl)acrylate
- CBNumber:
- CB9349146
- Molecular Formula:
- C12H11NO3
- Molecular Weight:
- 217.22
- MDL Number:
- MFCD00188426
- MOL File:
- 6935-44-0.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Ethyl 2-cyano-3-(4-hydroxyphenyl)acrylate ≥95% | OR15088 | 1g | $33 |
| (E)-Ethyl 2-cyano-3-(4-hydroxyphenyl)acrylate 97% | AS113591 | 1g | $48 |
| (E)-Ethyl 2-cyano-3-(4-hydroxyphenyl)acrylate 97% | AS113591 | 5g | $105 |
| (E)-Ethyl 2-Cyano-3-(4-Hydroxyphenyl)Acrylate ≥97% | AA00608X | 50mg | $10 |
| (E)-Ethyl 2-Cyano-3-(4-Hydroxyphenyl)Acrylate ≥97% | AA00608X | 250mg | $11 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H312+H332-H315-H319-H335 |
| Precautionary statements | P271-P261-P280 |
| Hazard Codes | Xi |
| HazardClass | IRRITANT |
| HS Code | 2916120090 |
ETHYL-ALPHA-CYANO-4-HYDROXYCINNAMATE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR15088 | Ethyl 2-cyano-3-(4-hydroxyphenyl)acrylate ≥95% | 6935-44-0 | 1g | $33 | 2026-06-04 | Buy |
| Activate Scientific | AS113591 | (E)-Ethyl 2-cyano-3-(4-hydroxyphenyl)acrylate 97% | 6935-44-0 | 1g | $48 | 2026-06-04 | Buy |
| Activate Scientific | AS113591 | (E)-Ethyl 2-cyano-3-(4-hydroxyphenyl)acrylate 97% | 6935-44-0 | 5g | $105 | 2026-06-04 | Buy |
| aablocks | AA00608X | (E)-Ethyl 2-Cyano-3-(4-Hydroxyphenyl)Acrylate ≥97% | 6935-44-0 | 50mg | $10 | 2026-05-28 | Buy |
| aablocks | AA00608X | (E)-Ethyl 2-Cyano-3-(4-Hydroxyphenyl)Acrylate ≥97% | 6935-44-0 | 250mg | $11 | 2026-05-28 | Buy |
ETHYL-ALPHA-CYANO-4-HYDROXYCINNAMATE Chemical Properties,Uses,Production
Chemical Properties
Light-yellow crystalline powder
Synthesis
123-08-0
105-56-6
42205-38-9
GENERAL METHODS: 5 mmol of p-hydroxybenzaldehyde was added to a round-bottomed flask with 5 mmol of ethyl cyanoacetate, 25 mg of polymer-loaded catalyst (0.5 mol% substrate) and 5 mL of anhydrous ethanol, and the reaction was stirred at room temperature. The reaction process was monitored by silica gel thin layer chromatography (TLC) with hexane-ethyl acetate (10:1) as eluent. Upon completion of the reaction, the reaction mixture was filtered using filter paper and the catalyst on the filter paper was washed several times with ethanol. The washings and filtrates were combined and the product was isolated after concentration under reduced pressure. Typically, the products were of high purity and did not require further purification. All the products were reported in literature and characterized by melting point determination, Fourier transform infrared spectroscopy (FTIR) and nuclear magnetic resonance hydrogen spectroscopy (1H NMR).
References
[1] Tetrahedron Letters, 2014, vol. 55, # 15, p. 2352 - 2354
[2] Synlett, 2016, vol. 27, # 9, p. 1433 - 1437
[3] Tetrahedron, 2000, vol. 56, # 47, p. 9357 - 9364
[4] Synthetic Communications, 2003, vol. 33, # 5, p. 783 - 788
[5] Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2010, vol. 49, # 3, p. 390 - 393
ETHYL-ALPHA-CYANO-4-HYDROXYCINNAMATE Preparation Products And Raw materials
ETHYL-ALPHA-CYANO-4-HYDROXYCINNAMATE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30224 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52704 | 58 |
| CR Corporation Limited | +8613062833949 | fred.wen@crcorporation.cn | China | 8645 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; | peter68@ptchemgroup.com | China | 35425 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49940 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
| DONBOO AMINO ACID COMPANY | +8618051385538 | donboo@donboo.com | China | 9363 | 58 |
| ORGANICA Feinchemie GmbH | +49 3494636389 | info@organica.de | Germany | 598 | 65 |
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