2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone
- CAS No.
- 106797-53-9
- Chemical Name:
- 2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone
- Synonyms
- Irgacure 2959;I2959;darocur2959;photoinitiator 2959;UV2959;HRcure-2959;2-hydroxy-4'-hydroxyethoxy-2-methylpropiophenone;2-hydroxy-1-(4-(2-hydroxyethoxy)phenyl)-2-methyl-1-propanone;1-Propanone, 2-hydroxy-1-4-(2-hydroxyethoxy)phenyl-2-methyl-;2-hydroxy-1-[4-(2-hydroxyethoxy)phenyl]-2-Methylpropan-1-one
- CBNumber:
- CB9415799
- Molecular Formula:
- C12H16O4
- Molecular Weight:
- 224.25
- MDL Number:
- MFCD00085267
- MOL File:
- 106797-53-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 2-Hydroxy-4′-(2-hydroxyethoxy)-2-methylpropiophenone 98% | 410896 | 10g | $73 |
| 2-Hydroxy-4′-(2-hydroxyethoxy)-2-methylpropiophenone 98% | 410896 | 50g | $251 |
| 2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone >98.0%(HPLC) | H1361 | 5g | $43 |
| 2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone >98.0%(HPLC) | H1361 | 25g | $128 |
| 2-Hydroxy-4''-(2-hydroxyethoxy)-2-methylpropiophenone ≥98% | 36428 | 5g | $44 |
| More product size | |||
| Melting point | 88-90 °C(lit.) |
|---|---|
| Boiling point | 405.0±25.0 °C(Predicted) |
| Density | 1.183±0.06 g/cm3(Predicted) |
| vapor pressure | 0Pa at 25℃ |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| form | powder to crystal |
| pka | 12.96±0.29(Predicted) |
| color | White to Light yellow |
| Water Solubility | 7.6g/L at 25℃ |
| Cosmetics Ingredients Functions | REDUCING |
| InChI | InChI=1S/C12H16O4/c1-12(2,15)11(14)9-3-5-10(6-4-9)16-8-7-13/h3-6,13,15H,7-8H2,1-2H3 |
| InChIKey | GJKGAPPUXSSCFI-UHFFFAOYSA-N |
| SMILES | C(C1=CC=C(OCCO)C=C1)(=O)C(O)(C)C |
| LogP | 0.84 at 23℃ |
| CAS DataBase Reference | 106797-53-9(CAS DataBase Reference) |
| Indirect Additives used in Food Contact Substances | 2-HYDROXY-1-(4-(2-HYDROXYETHOXY)PHENYL)-2-METHYL-1-PROPANONE |
| FDA 21 CFR | 175.105 |
| EPA Substance Registry System | 1-Propanone, 2-hydroxy-1-[4-(2-hydroxyethoxy)phenyl]-2-methyl- (106797-53-9) |
| UNSPSC Code | 12162002 |
| NACRES | NA.23 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H411 | |||||||||
| Precautionary statements | P273-P391-P501 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | UC2976000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29145090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Aquatic Chronic 2 | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone price More Price(43)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 410896 | 2-Hydroxy-4′-(2-hydroxyethoxy)-2-methylpropiophenone 98% | 106797-53-9 | 10g | $73 | 2026-04-30 | Buy |
| Sigma-Aldrich | 410896 | 2-Hydroxy-4′-(2-hydroxyethoxy)-2-methylpropiophenone 98% | 106797-53-9 | 50g | $251 | 2026-04-30 | Buy |
| TCI Chemical | H1361 | 2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone >98.0%(HPLC) | 106797-53-9 | 5g | $43 | 2026-04-30 | Buy |
| TCI Chemical | H1361 | 2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone >98.0%(HPLC) | 106797-53-9 | 25g | $128 | 2026-04-30 | Buy |
| Cayman Chemical | 36428 | 2-Hydroxy-4''-(2-hydroxyethoxy)-2-methylpropiophenone ≥98% | 106797-53-9 | 5g | $44 | 2026-04-30 | Buy |
2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone Chemical Properties,Uses,Production
Description
2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone(Photoinitiator 2959) has been tested for use in UV curing formulations on wood, metal, plastic and paper surfaces.It has lower volatility and odor compared to Irgacure 1173. Importantly, the reactive hydroxyl groups of it are easily grafted onto the polymer molecules, making it more convenient to process.
Uses
2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone is a photoinitiator allowed by the FDA certification system; it can be used in water-based photocuring systems, with high melting point, and can also be used in UV-curable powder coatings; it is a high-efficiency non-yellowing UV photoinitiator. UV polymerization of saturated prepolymerized systems.
Chemical Properties
Density 1.183 g/cm3, melting point 88-90°C (lit.), boiling point 405℃ at 760 mmH, flash point 155.8℃, refractive index .544, vapor pressure 2.75E-07 mmHg at 25℃.
Uses
2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone is used in the preparation of UV-VIS curable PEG hydrogels for biomedical applications with multi-functionality.
Definition
ChEBI: 2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone is an aromatic ketone.
Synthesis
![1-Propanone, 1-[4-(2-hydroxyethoxy)phenyl]-2-methyl-](/CAS/20210111/GIF/159119-01-4.gif)
159119-01-4
106797-53-9
The general procedure for the synthesis of photoinitiator 2959 from the compound (CAS:159119-01-4) was as follows: a 25 mL Schlenk reaction tube was taken and N-bromosuccinimide (NBS) 18 mg (0.1 mmol) was added sequentially as catalyst, 4'-(2-hydroxyethoxy)-2-methylpropiophenone 105 mg (0.5 mmol), and dimethyl sulfoxide (DMSO) 1 mL as oxidizing reagent and solvent. ), and dimethyl sulfoxide (DMSO) 1 mL as oxidizer, carbonylation reagent and solvent. The reaction mixture was stirred at 100 °C for 24 hours. Upon completion of the reaction, 15 mL of ethyl acetate and 3 mL of brine were added to the reaction mixture for extraction, which was then extracted three times with ethyl acetate. All organic phases were combined and purified by column chromatographic separation to give a final purity of 103 mg of 2-hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone in 92% yield.
References
[1] Organic Letters, 2015, vol. 17, # 4, p. 876 - 879
[2] Patent: CN104710256, 2017, B. Location in patent: Paragraph 0174-0177
[3] Angewandte Chemie - International Edition, 2014, vol. 53, # 2, p. 548 - 552
[4] Angew. Chem., 2014, vol. 53, # 2, p. 558 - 562,5
[5] Patent: CN107739303, 2018, A. Location in patent: Paragraph 0017
2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangxi Lotchem Co.,Ltd. | +8615270827708 | lancetu@jxlotchem.com | CHINA | 338 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +86-15350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +86-17531190177 | faithe@yan-xi.com | China | 5853 | 58 |
| Shanghai UCHEM Inc. | +86-18930848214 +86-021-56762820 | sales@myuchem.com | China | 8886 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 | sales1@chuanghaibio.com | China | 5218 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +86-17732866630 | mina@chuanghaibio.com | China | 18126 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 | deasea125996@gmail.com | China | 2472 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | 13343047651 | admin@zlchemi.com | China | 3692 | 58 |
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-15225627621 +86-13213167925 | jiuyitime@fdachem.com | China | 16511 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14026 | 58 |
View Lastest Price from 2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-08-03 | 2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone
106797-53-9
|
$127.00 | 1kg | 0.99 | 25kg | Shanghai UCHEM Inc. | |
 |
2026-08-03 | 2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone/IHT-PI 659
106797-53-9
|
1Kg/Bag | 98%min | 1000KG | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-07-31 | 2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone
106797-53-9
|
1kg/Bag | ≥98% | 50 T/Month | Hebei Qujie Technology Co., Ltd. |
-
- 2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone
106797-53-9
- $127.00
- 0.99
- Shanghai UCHEM Inc.
-
- 2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone/IHT-PI 659
106797-53-9
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone
106797-53-9
- $0.00
- ≥98%
- Hebei Qujie Technology Co., Ltd.
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