6-BROMO-2(1H)-QUINOLONE
- CAS No.
- 1810-66-8
- Chemical Name:
- 6-BROMO-2(1H)-QUINOLONE
- Synonyms
- 6-BROMOQUINOLIN-2(1H)-ONE;6-bromoquinolin-2-ol;6-BROMO-2-QUINOLONE;6-BroMo-1H-quinolin-2-one;2-Hydroxy-6-bromoquinoline;P-524;109404;6-Bromocarbostyril;6-Bromo-2-quinolinol;6-bromoquinolin-2-one
- CBNumber:
- CB9763838
- Molecular Formula:
- C9H6BrNO
- Molecular Weight:
- 224.05
- MDL Number:
- MFCD08703169
- MOL File:
- 1810-66-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 2-Hydroxy-6-bromoquinoline Aldrich | BBO000085 | 1g | $230 |
| 6-Bromo-2(1H)-quinolinone | TRC-B686950-1G | 1g | $123 |
| 6-BROMOQUINOLIN-2(1H)-ONE 95% | SC2991 | 1G | $32 |
| 6-BROMOQUINOLIN-2(1H)-ONE 95% | SC2991 | 5G | $95 |
| 6-BROMOQUINOLIN-2(1H)-ONE 95% | SC2991 | 25G | $284 |
| More product size | |||
| Melting point | 278-280C |
|---|---|
| Boiling point | 393.8±42.0 °C(Predicted) |
| Density | 1.620±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO |
| pka | 10.76±0.70(Predicted) |
| form | Solid |
| color | Beige |
| InChI | InChI=1S/C9H6BrNO/c10-7-2-3-8-6(5-7)1-4-9(12)11-8/h1-5H,(H,11,12) |
| InChIKey | YLAFBGATSQRSTB-UHFFFAOYSA-N |
| SMILES | N1C2=C(C=C(Br)C=C2)C=CC1=O |
| UNSPSC Code | 12352200 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H318 | |||||||||
| Precautionary statements | P264-P270-P280-P301+P312-P305+P351+P338-P501 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-41 | |||||||||
| Safety Statements | 26-39 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 2933499090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Dam. 1 |
|||||||||
| NFPA 704 |
|
6-BROMO-2(1H)-QUINOLONE price More Price(61)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | BBO000085 | 2-Hydroxy-6-bromoquinoline Aldrich | 1810-66-8 | 1g | $230 | 2026-04-30 | Buy |
| TRC | TRC-B686950-1G | 6-Bromo-2(1H)-quinolinone | 1810-66-8 | 1g | $123 | 2026-06-03 | Buy |
| AstaTech | SC2991 | 6-BROMOQUINOLIN-2(1H)-ONE 95% | 1810-66-8 | 1G | $32 | 2026-04-30 | Buy |
| AstaTech | SC2991 | 6-BROMOQUINOLIN-2(1H)-ONE 95% | 1810-66-8 | 5G | $95 | 2026-04-30 | Buy |
| AstaTech | SC2991 | 6-BROMOQUINOLIN-2(1H)-ONE 95% | 1810-66-8 | 25G | $284 | 2026-04-30 | Buy |
6-BROMO-2(1H)-QUINOLONE Chemical Properties,Uses,Production
Chemical Properties
Beige Solid
Uses
6-Bromo-2(1H)-quinolinone is a useful intermediate for the synthesis of other quinoline derivatives.
Synthesis
327058-51-5
1810-66-8
General procedure for the synthesis of 6-bromoquinolin-2(1H)-one from the compound (CAS:327058-51-5): 6-bromo-2(1H)-quinolinone (6.0 g, 22.2 mmol) was dissolved in concentrated H2SO4 (30 mL) and the reaction was heated in an oil bath at 100 °C overnight. Upon completion of the reaction, the mixture was cooled to room temperature and quenched with ice water. The precipitate precipitated was collected by filtration, washed with water and subsequently dried under vacuum to afford 6-bromoquinolin-2(1H)-one as a white solid (4.8 g, 97% yield). Mass spectrum (ES+) m/e 225 [M+H]+.
References
[1] Patent: WO2006/132739, 2006, A2. Location in patent: Page/Page column 35-36
[2] Chemical and Pharmaceutical Bulletin, 2014, vol. 62, # 6, p. 508 - 518
[3] European Journal of Medicinal Chemistry, 2000, vol. 35, # 10, p. 931 - 940
[4] Journal of Medicinal Chemistry, 2005, vol. 48, # 1, p. 306 - 311
6-BROMO-2(1H)-QUINOLONE Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14026 | 58 |
| Chembon Pharmaceutical Co., Ltd. | +86-28-8425-2981 | CHINA | 722 | 55 | |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29812 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 +86-18019713315 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49979 | 58 | |
| Fuxin Pharmaceutical | +86-021-021-50872116 | contact@fuxinpharm.com | China | 9976 | 58 |
View Lastest Price from 6-BROMO-2(1H)-QUINOLONE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-11-18 | 6-BROMO-2(1H)-QUINOLONE
1810-66-8
|
$1.10 | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited | |
 |
2019-07-07 | 6-BROMO-2(1H)-QUINOLONE
1810-66-8
|
$1.00 | 1KG | 99% | 100kg | Career Henan Chemical Co | |
 |
2018-09-26 | 6-Bromo-2(1H)-quinolone;2-Hydroxy-6-bromoquinoline;6-Bromo-2(1H)-quinolinone ada@tuskwei.com
1810-66-8
|
$3.00 | 1G | 99% | 7000g/day ada@tuskwei.com whatsapp;+08617197824028 | Hebei Jiangkai Trading Co., Ltd
|
-
- 6-BROMO-2(1H)-QUINOLONE
1810-66-8
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 6-BROMO-2(1H)-QUINOLONE
1810-66-8
- $1.00
- 99%
- Career Henan Chemical Co
-
- 6-Bromo-2(1H)-quinolone;2-Hydroxy-6-bromoquinoline;6-Bromo-2(1H)-quinolinone ada@tuskwei.com
1810-66-8
- $3.00
- 99%
- Hebei Jiangkai Trading Co., Ltd
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