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ChemicalBook >> CAS DataBase List >>2-Fluorobenzamide

2-Fluorobenzamide

CAS No.
445-28-3
Chemical Name:
2-Fluorobenzamide
Synonyms
Benzamide, 2-fL;o-fluoro-benzamid;2-fluoro-benzamid;2-FLUOROBENZAMIDE;O-FLUOROBENZAMIDE;Benzamide, 2-fluoro-;2-Fluorobenzamide>ortho-Fluorobenzamide;2-Fluorobenzamide,98%;LABOTEST-BB LT00848244
CBNumber:
CB9770193
Molecular Formula:
C7H6FNO
Molecular Weight:
139.13
MDL Number:
MFCD00007970
MOL File:
445-28-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 06:09:43
Product description Number Pack Size Price
2-Fluorobenzamide >98.0%(T) F0278 10g $127
2-Fluorobenzamide TRC-F598015-500MG 500mg $123
2-Fluorobenzamide TRC-F598015-1G 1g $163
2-Fluorobenzamide TRC-F598015-100MG 100mg $97
2-Fluorobenzamide 98% PC3472 5g $54
More product size

2-Fluorobenzamide Properties

Melting point 117-119 °C (lit.)
Boiling point 238.4±23.0 °C(Predicted)
Density 1.2099 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), DMSO (Slightly)
form powder to crystal
pka 15.27±0.50(Predicted)
color White to Almost white
BRN 2325863
InChI InChI=1S/C7H6FNO/c8-6-4-2-1-3-5(6)7(9)10/h1-4H,(H2,9,10)
InChIKey KGGHWIKBOIQEAJ-UHFFFAOYSA-N
SMILES C(N)(=O)C1=CC=CC=C1F
CAS DataBase Reference 445-28-3(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII HM4GB9599U
NIST Chemistry Reference Benzamide, 2-fluoro-(445-28-3)
EPA Substance Registry System Benzamide, 2-fluoro- (445-28-3)
UNSPSC Code 12352100

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  37/39-26-24/25
WGK Germany  3
RTECS  CV4953333
HazardClass  IRRITANT
HS Code  29242990
Storage Class 11 - Combustible Solids
NFPA 704
0
1 0

2-Fluorobenzamide price More Price(44)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical F0278 2-Fluorobenzamide >98.0%(T) 445-28-3 10g $127 2026-04-30 Buy
TRC TRC-F598015-500MG 2-Fluorobenzamide 445-28-3 500mg $123 2026-06-03 Buy
TRC TRC-F598015-1G 2-Fluorobenzamide 445-28-3 1g $163 2026-06-03 Buy
TRC TRC-F598015-100MG 2-Fluorobenzamide 445-28-3 100mg $97 2026-06-03 Buy
Apolloscientific PC3472 2-Fluorobenzamide 98% 445-28-3 5g $54 2026-06-04 Buy
Product number Packaging Price Buy
F0278 10g $127 Buy
TRC-F598015-500MG 500mg $123 Buy
TRC-F598015-1G 1g $163 Buy
TRC-F598015-100MG 100mg $97 Buy
PC3472 5g $54 Buy

2-Fluorobenzamide Chemical Properties,Uses,Production

Chemical Properties

white crystalline powder

Uses

2-Fluorobenzamide can be useful in microwave assisted preparation of oxazole-dehydrozingerone based hybrid molecules as anti-tubercular agents and their docking for Mtb DNA gyrase.

General Description

2-Fluorobenzamide inhibits the activity of poly(ADP-ribose) synthetase in vitro. It undergoes coupling with anilines in the presence of lithium amides to yield N-arylanthranilamides.

Synthesis

Benzaldehyde, 2-fluoro-, oxime, (E)- (9CI)

24652-66-2

2-Fluorobenzamide

445-28-3

The general procedure for the synthesis of o-fluorobenzamide from (E)-2-fluorobenzaldehyde oxime was as follows: (E)-2-fluorobenzaldehyde oxime (69.6 mg, 0.5 mmol) and [Cp*Ir(H2O)3][OTf]2 (5.1 mg, 0.0075 mmol) were added sequentially to a 25 mL Schlenk reaction flask. The reaction mixture was stirred at 110 °C for 12 hours. After completion of the reaction, the mixture was cooled to room temperature and the solvent was removed by rotary evaporation. The crude product was purified by column chromatography to give o-fluorobenzamide in 83% yield. The structure of the product was confirmed by nuclear magnetic resonance hydrogen (1H NMR) and carbon (13C NMR) spectra: 1H NMR (400 MHz, DMSO-d6) δ 7.54-7.50 (m, 1H, ArH), 7.29-7.25 (m, 3H, ArH); 13C NMR (100 MHz, DMSO-d6) δ 162.3 (d, JCF = 247.7 Hz), 132.4 (d, JCF = 8.8 Hz), 130.1 (d, JCF = 6.6 Hz), 124.3 (d, JCF = 2.6 Hz), 123.8 (d, JCF = 14.0 Hz), 116.0 (d, JCF = 22.5 Hz).

References

[1] RSC Advances, 2016, vol. 6, # 43, p. 37093 - 37098
[2] Organometallics, 2012, vol. 31, # 17, p. 6482 - 6490
[3] Catalysis Science and Technology, 2014, vol. 4, # 4, p. 988 - 996
[4] Patent: CN104418682, 2016, B. Location in patent: Paragraph 0047-0050

Global( 185)Suppliers
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View Lastest Price from 2-Fluorobenzamide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Fluorobenzamide  pictures 2025-12-12 2-Fluorobenzamide
445-28-3
$1.00-28.00 1KG 99% 20000KG Shaanxi Dideu Medichem Co. Ltd
2-Fluorobenzamide pictures 2022-02-19 2-Fluorobenzamide
445-28-3
1KG 97.1% 100 tons Honest Joy Holdings Limited
2-Fluorobenzamide pictures 2019-07-06 2-Fluorobenzamide
445-28-3
$1.00 1kg 95%-99% 100kg Career Henan Chemical Co
2-fluoro-benzamid o-fluoro-benzamid ortho-Fluorobenzamide O-FLUOROBENZAMIDE 2-FLUOROBENZAMIDE LABOTEST-BB LT00848244 2-Fluorobenzamide o-Fluorobenzamide 2-Fluorobenzamide,98% O-fluorophenyl forMaMide 2-FluorobenzaMide, 98% 5GR (2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(4H-imid Benzamide, 2-fluoro- 2-Fluorobenzamide> Benzamide, 2-fL 445-28-3 C7H6NOF Amides Building Blocks Carbonyl Compounds Organic Building Blocks Anilines, Amides & Amines Fluorine Compounds Amides Carbonyl Compounds Organic Building Blocks
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