4-TERT-BUTYL-3,6-DICHLOROPYRIDAZINE
- CAS No.
- 22808-29-3
- Chemical Name:
- 4-TERT-BUTYL-3,6-DICHLOROPYRIDAZINE
- Synonyms
- 4-TERT-BUTYL-3,6-DICHLOROPYRIDAZINE;3,6-Dichloro-4-tert-butylpyridazine;Pyridazine, 4-tert-butyl-3,6-dichloro-;3,6-Dichloro-4-(1,1-dimethylethyl)pyridazine;Pyridazine, 3,6-dichloro-4-(1,1-dimethylethyl)-;4-TERT-BUTYL-3,6-DICHLOROPYRIDAZINE ISO 9001：2015 REACH
- CBNumber:
- CB9823118
- Molecular Formula:
- C8H10Cl2N2
- Molecular Weight:
- 205.08
- MDL Number:
- MFCD01938756
- MOL File:
- 22808-29-3.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4-tert-Butyl-3,6-dichloropyridazine 97% | AS33528 | 1g | $90 |
| 4-tert-Butyl-3,6-dichloropyridazine 97% | AS33528 | 5g | $316 |
| 4-tert-Butyl-3,6-dichloropyridazine 97% | AS33528 | 25g | $977 |
| 4-tert-Butyl-3,6-dichloropyridazine | 071151 | 5.00g | $615 |
| 4-tert-Butyl-3,6-dichloropyridazine ≥97% | AA007NMW | 50mg | $10 |
| More product size | |||
| Melting point | 37-40 °C |
|---|---|
| Boiling point | 297.3±35.0 °C(Predicted) |
| Density | 1.231 |
| refractive index | 1.52 |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | Chloroform, Dichloromethane |
| form | Oil |
| pka | -0.40±0.10(Predicted) |
| color | Colourless |
| EWG's Food Scores | 1 |
| EPA Substance Registry System | Pyridazine, 3,6-dichloro-4-(1,1-dimethylethyl)- (22808-29-3) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| Toxicity | rat,LDLo,oral,500mg/kg (500mg/kg),SENSE ORGANS AND SPECIAL SENSES: CHROMODACYRORREA: EYEBEHAVIORAL: COMABEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD,National Technical Information Service. Vol. OTS0544009, |
4-TERT-BUTYL-3,6-DICHLOROPYRIDAZINE price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS33528 | 4-tert-Butyl-3,6-dichloropyridazine 97% | 22808-29-3 | 1g | $90 | 2026-06-04 | Buy |
| Activate Scientific | AS33528 | 4-tert-Butyl-3,6-dichloropyridazine 97% | 22808-29-3 | 5g | $316 | 2026-06-04 | Buy |
| Activate Scientific | AS33528 | 4-tert-Butyl-3,6-dichloropyridazine 97% | 22808-29-3 | 25g | $977 | 2026-06-04 | Buy |
| Matrix Scientific | 071151 | 4-tert-Butyl-3,6-dichloropyridazine | 22808-29-3 | 5.00g | $615 | 2026-05-18 | Buy |
| aablocks | AA007NMW | 4-tert-Butyl-3,6-dichloropyridazine ≥97% | 22808-29-3 | 50mg | $10 | 2026-05-28 | Buy |
4-TERT-BUTYL-3,6-DICHLOROPYRIDAZINE Chemical Properties,Uses,Production
Chemical Properties
Colourless Oil
Synthesis
141-30-0
75-98-9
22808-29-3
Synthesis of compound J.1. To a 250 mL round bottom flask was added 3,6-dichloropyridazine (1.49 g, 10 mmol, 1.0 eq.), silver nitrate (0.17 g, 1 mmol, 0.1 eq.), deionized water (30 mL), pivalic acid (3.57 g, 35 mmol, 3.5 eq.), and concentrated sulfuric acid (1.6 mL, 30 mmol, 3.0 eq.). The reaction mixture was heated to 70 °C and kept at a constant temperature. An aqueous solution (10 mL) of ammonium persulfate (2.28 g, 10 mmol, 1.0 eq.) was added slowly and dropwise over 10 minutes. After the dropwise addition, the reaction was continued with stirring at 70 °C for 1 hour. After completion of the reaction, the mixture was cooled to room temperature. The reaction mixture was slowly poured into ice water (100 mL) and the pH was adjusted with aqueous ammonium hydroxide to 8. The aqueous phase was extracted with dichloromethane (3 × 250 mL). The organic phases were combined, filtered through a cotton plug, washed with 1N aqueous NaOH (70 mL), dried over anhydrous magnesium sulfate, and concentrated under reduced pressure. Purification of the crude product by fast column chromatography (20% ethyl acetate/hexane) afforded 4-tert-butyl-3,6-dichloropyridazine (1.32 g, 64% yield) as a white solid.1H NMR (400 MHz, CDCl3) δ: 7.5 (s, 1H), 1.5 (s, 9H); Rf = 0.5 (80% ethyl acetate/hexane).
References
[1] Patent: US2009/5359, 2009, A1. Location in patent: Page/Page column 39
[2] Patent: US2009/36419, 2009, A1. Location in patent: Page/Page column 84
[3] Journal of Medicinal Chemistry, 2005, vol. 48, # 23, p. 7089 - 7092
[4] Bioorganic and Medicinal Chemistry Letters, 2010, vol. 20, # 20, p. 6030 - 6033
4-TERT-BUTYL-3,6-DICHLOROPYRIDAZINE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30224 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 28760 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52704 | 58 |
| Golden Pharma Co., Limited | +undefined18958062155 | sales@zjgoldpharm.com | China | 5899 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49954 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Suzhou ARTK Medchem Co., Ltd. | +8618118463618 | sales1@artkmedchem.com | China | 39021 | 58 |
View Lastest Price from 4-TERT-BUTYL-3,6-DICHLOROPYRIDAZINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-11-18 | 4-TERT-BUTYL-3,6-DICHLOROPYRIDAZINE
22808-29-3
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited |
-
- 4-TERT-BUTYL-3,6-DICHLOROPYRIDAZINE
22808-29-3
- $1.10
- 99.00%
- Dideu Industries Group Limited
