BIS(2-BROMOETHYL)AMINE HYDROBROMIDE
- CAS No.
- 43204-63-3
- Chemical Name:
- BIS(2-BROMOETHYL)AMINE HYDROBROMIDE
- Synonyms
- Trazodone Impurity Y;BIS(2-BROMOETHYL)AMINE HBR;Vortioxetine Impurity 36 HBr;bis(2-bromoethyl)ammonium bromide;Bis(2-bromoethyl)amine hydrobromide;2,2'-Dibromodiethylamine Hydrobromide;Bis(2-bromoethyl)amine·hydrobrominate;Bis(2-bromoethyl)ammonium hydrobromide;2-Bromo-N-(2-bromoethyl)ethanamine HBr;BIS(2-BROMOETHYL)AMINEHYDROBROMICACIDSALT
- CBNumber:
- CB9886344
- Molecular Formula:
- C4H10Br3N
- Molecular Weight:
- 311.8409
- MDL Number:
- MFCD11044002
- MOL File:
- 43204-63-3.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Bis(2-Bromoethyl)amine hydrobromide | 076029 | 1.00g | $74 |
| Bis(2-Bromoethyl)amine hydrobromide | 076029 | 5.00g | $222 |
| Bis(2-Bromoethyl)amine hydrobromide 90+% | B28721 | 250mg | $70 |
| Bis(2-Bromoethyl)amine hydrobromide 90+% | B28721 | 1g | $130 |
| Bis(2-Bromoethyl)amine hydrobromide 90+% | B28721 | 5g | $650 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
BIS(2-BROMOETHYL)AMINE HYDROBROMIDE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 076029 | Bis(2-Bromoethyl)amine hydrobromide | 43204-63-3 | 1.00g | $74 | 2026-05-18 | Buy |
| Matrix Scientific | 076029 | Bis(2-Bromoethyl)amine hydrobromide | 43204-63-3 | 5.00g | $222 | 2026-05-18 | Buy |
| Synthonix | B28721 | Bis(2-Bromoethyl)amine hydrobromide 90+% | 43204-63-3 | 250mg | $70 | 2026-05-06 | Buy |
| Synthonix | B28721 | Bis(2-Bromoethyl)amine hydrobromide 90+% | 43204-63-3 | 1g | $130 | 2026-05-06 | Buy |
| Synthonix | B28721 | Bis(2-Bromoethyl)amine hydrobromide 90+% | 43204-63-3 | 5g | $650 | 2026-05-06 | Buy |
BIS(2-BROMOETHYL)AMINE HYDROBROMIDE Chemical Properties,Uses,Production
Uses
2,2''-Dibromodiethylamine Hydrobromide is used in the synthesis of quinone phosphorodiamidate drugs that target DT-diaphorase, an enzyme that is overexpressed in solid tumors. Also used in the preparation of anti-depressive drugs, in the treatment of major depressive disorders. Trazadone Impurity.
Uses
Bis(2-bromoethyl)amine hydrobromide is used in the synthesis of quinone phosphorodiamidate drugs that target DT-diaphorase, an enzyme that is overexpressed in solid tumors. Also used in the preparat ion of anti-depressive drugs, in the treatment of major depressive disorders. Trazadone Impurity.
Synthesis
111-42-2
43204-63-3
The general procedure for the synthesis of bis(2-bromoethyl)amine hydrobromide from diethanolamine is as follows: 157.5 g (1.5 mol) of diethanolamine is added to a 2-liter three-necked flask equipped with a refluxing or distillation apparatus. 1.35 liters of 48% hydrobromic acid is slowly added with stirring (note: this process is exothermic). The reaction mixture was heated in an oil bath at 180-200°C with a controlled vapor temperature of 122°C until 350 ml of liquid was distilled. Subsequently, the unit was adjusted to reflux and kept for 1 hour. The distillation process was repeated and 465 ml of distillate was collected. The unit was again adjusted to reflux and maintained for 3.75 hours before 400 ml of liquid was distilled. After completion of the reaction, the mixture was cooled and 300 ml of ethyl acetate was added to the residue. The resulting suspension was stirred in an ice bath for 1 hour. The precipitate was collected by filtration and washed with ethyl acetate. A final 367 g of white crystalline product was obtained in 78.5% yield with a melting point of 130-135°C.
References
[1] Patent: US2004/266802, 2004, A1. Location in patent: Page 7-8
[2] Patent: US5233031, 1993, A
[3] Journal of Medicinal Chemistry, 2000, vol. 43, # 16, p. 3157 - 3167
[4] Patent: US2007/259883, 2007, A1. Location in patent: Page/Page column 6; 9
BIS(2-BROMOETHYL)AMINE HYDROBROMIDE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10403 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49979 | 58 | |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29792 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 | contact@fuxinpharm.com | China | 9976 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +86-18530059196 | sale04@alfachem.cn | China | 9612 | 58 |
| Chemsigma International Co., Ltd. | +86-2558742998 +86-19951791336 | info@chemsigma.com | China | 1817 | 58 |
| AFINE CHEMICALS LIMITED | +86-571-85134551 +86-18958018566 | info@afinechem.com | China | 15079 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 | sales@sarms4muscle.com | China | 10457 | 58 |
| CR Corporation Limited | fred.wen@crcorporation.cn | China | 8645 | 58 |
View Lastest Price from BIS(2-BROMOETHYL)AMINE HYDROBROMIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-04 | bis(2-bromoethyl)ammonium bromide
43204-63-3
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | ||
 |
2019-12-20 | BIS(2-BROMOETHYL)AMINE HYDROBROMIDE
43204-63-3
|
$1.00 | 1g | 85.0-99.8% | 20 tons | Career Henan Chemical Co |
-
- bis(2-bromoethyl)ammonium bromide
43204-63-3
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- BIS(2-BROMOETHYL)AMINE HYDROBROMIDE
43204-63-3
- $1.00
- 85.0-99.8%
- Career Henan Chemical Co
