スピロジクロフェン 化學(xué)特性,用途語,生産方法
外観
白色, 結(jié)晶性粉末?粉末
溶解性
エタノール及びアセトンに溶け、水にほとんど溶けない。
用途
ACCase阻害型殺蟲剤?殺ダニ剤ハダニ類などに活性を示す
農(nóng)薬用途
ダニ駆除剤
説明
Spirodiclofen is a new selective, non systemic acaricide belonging to the chemical group of the spirocyclic tetronic acid derivatives. It acts by interfering with mite development, thereby controlling such pests as Panonychus spp., Phyllocoptruta spp., Brevipalpus spp., and Aculus and Tetranychus species. Spirodiclofen is active by contact to mite eggs, all nymphal stages, and adult females (adult males are not effected). Spirodiclofen is structurally similar to spiromesifen, which is also a tetronic acid insecticide. Spirodiclofen is registered worldwide for use on a variety of crops including citrus, pome fruits, stone fruits, grapes and ornamentals.
定義
ChEBI: Spirodiclofen is an organochlorine acaricide, a dichlorobenzene, an oxaspiro compound and a gamma-lactone. It derives from a 1,3-dichlorobenzene.
作用機制
昆蟲やダニの脂質(zhì)生合成を阻害する
合成
Spirodiclofen is commercially produced via a multi-step synthesis starting with the condensation of 2,2-dimethyl-1,3-dioxane-4,6-dione (Meldrum’s acid) with 3-(2,4-dichlorophenyl)propanoyl chloride under basic conditions to form an intermediate enol ester, which undergoes thermal cyclisation in the presence of 1,1,1-trichloroethane or similar solvent to yield the spirocyclic core; subsequent esterification with 2,2-dimethylbutyryl chloride and purification give the active compound.
Mode of action
Spirodiclofen is a progenitor of tetronic acid derivates (inhibitors of acetyl CoA carboxylase), characterized by an original (unique) mechanism of action which combines long-lasting protection with anthocorid safety for effective integrated pest management.
It interferes/inhibits the lipid biosynthesis of Mites, Mealybugs and Pear-psylla.
スピロジクロフェン 上流と下流の製品情報
原材料
準(zhǔn)備製品