硝酸イソソルビド 化學(xué)特性,用途語,生産方法
用途
冠拡張薬、血管拡張薬、利尿薬
効能
冠血管拡張薬
商品名
ニトロール (エーザイ); ニトロール (エーザイ); ニトロール (エーザイ); ニトロール (エーザイ); ニトロール (エーザイ); ニトロール (エーザイ); ニトロール (エーザイ); フランドル (トーアエイヨー); フランドル (トーアエイヨー); 硝酸イソソルビド (メディサ新薬)
化學(xué)的特性
white to light yellow crystal powde
使用
Isosorbide dinitrate is also used in chronic cardiac insufficiency for preventing angina pectoris
attacks. It is a long-lasting drug.
一般的な説明
A crystalline solid. May be toxic by ingestion. Used to make pharmaceuticals. Used as a heart drug.
空気と水の反応
Highly flammable. Slightly soluble in water.
反応プロフィール
Nitroalkanes, such as Isosorbide dinitrate, range from slight to strong oxidizing agents. If mixed with reducing agents, including hydrides, sulfides and nitrides, they may begin a vigorous reaction that culminates in a detonation. Nitroalkanes are milder oxidizing agents, but still react violently with reducing agents at higher temperature and pressures. Nitroalkanes react with inorganic bases to form explosive salts. The presence of metal oxides increases the thermal sensitivity of nitroalkanes. Nitroalkanes with more than one nitro group are generally explosive. Nitroalkanes are insoluble in water. This heart drug is detonable when dry, but non-explosive with 30% of water.
健康ハザード
Fire may produce irritating and/or toxic gases. Contact may cause burns to skin and eyes. Contact with molten substance may cause severe burns to skin and eyes. Runoff from fire control may cause pollution.
火災(zāi)危険
Flammable/combustible material. May be ignited by friction, heat, sparks or flames. Some may burn rapidly with flare burning effect. Powders, dusts, shavings, borings, turnings or cuttings may explode or burn with explosive violence. Substance may be transported in a molten form at a temperature that may be above its flash point. May re-ignite after fire is extinguished.
安全性プロファイル
Moderately toxic by
ingestion, intraperitoneal, intramuscular, and
subcutaneous routes. Experimental
reproductive effects. Mutation data
reported. A flammable solid. When heated
to decomposition it emits toxic fumes of
NOx. A coronary vasodilator. See also
NITRATES.
硝酸イソソルビド 上流と下流の製品情報(bào)
原材料
準(zhǔn)備製品