4-(4-アミノフェノキシ)-N-メチル-2-ピリジンカルボキサミド
4-(4-アミノフェノキシ)-N-メチル-2-ピリジンカルボキサミド 物理性質(zhì)
- 融點(diǎn) :
- 110-112°C
- 沸點(diǎn) :
- 476.8±40.0 °C(Predicted)
- 比重(密度) :
- 1.241±0.06 g/cm3(Predicted)
- 蒸気圧:
- 0.001-0.05Pa at 20-109.84℃
- 貯蔵溫度 :
- Keep in dark place,Inert atmosphere,Room temperature
- 溶解性:
- DMSO (Slightly), Methanol (Slightly)
- 外見(jiàn) :
- solid
- 酸解離定數(shù)(Pka):
- 13.96±0.46(Predicted)
- 色:
- White to Light yellow to Light orange
- InChI:
- InChI=1S/C13H13N3O2/c1-15-13(17)12-8-11(6-7-16-12)18-10-4-2-9(14)3-5-10/h2-8H,14H2,1H3,(H,15,17)
- InChIKey:
- RXZZBPYPZLAEFC-UHFFFAOYSA-N
- SMILES:
- C1(C(NC)=O)=NC=CC(OC2=CC=C(N)C=C2)=C1
- LogP:
- 0.9 at 25℃ and pH7
- 表面張力:
- 71.71mN/m at 883.8mg/L and 20.1℃
4-(4-アミノフェノキシ)-N-メチル-2-ピリジンカルボキサミド 価格
もっと(22)
| メーカー |
製品番號(hào) |
製品説明 |
CAS番號(hào) |
包裝 |
価格 |
更新時(shí)間 |
購(gòu)入 |
|
富士フイルム和光純薬株式會(huì)社(wako)
|
W01APOOR303782 |
4-(4-アミノフェノキシ)-N-メチルピリジン-2-カルボキサミド
4-(4-Aminophenoxy)-N-methylpyridine-2-carboxamide |
284462-37-9 |
500mg |
￥89300 |
2024-03-01 |
購(gòu)入 |
|
富士フイルム和光純薬株式會(huì)社(wako)
|
W01APOOR303782 |
4-(4-アミノフェノキシ)-N-メチルピリジン-2-カルボキサミド
4-(4-Aminophenoxy)-N-methylpyridine-2-carboxamide |
284462-37-9 |
1g |
￥120000 |
2024-03-01 |
購(gòu)入 |
|
東京化成工業(yè)
|
A2617 |
4-(4-アミノフェノキシ)-N-メチル-2-ピリジンカルボキサミド >98.0%(HPLC)(T)
4-(4-Aminophenoxy)-N-methyl-2-pyridinecarboxamide
>98.0%(HPLC)(T) |
284462-37-9 |
1g |
￥1800 |
2024-03-01 |
購(gòu)入 |
|
東京化成工業(yè)
|
A2617 |
4-(4-アミノフェノキシ)-N-メチル-2-ピリジンカルボキサミド >98.0%(HPLC)(T)
4-(4-Aminophenoxy)-N-methyl-2-pyridinecarboxamide
>98.0%(HPLC)(T) |
284462-37-9 |
5g |
￥4700 |
2024-03-01 |
購(gòu)入 |
|
富士フイルム和光純薬株式會(huì)社(wako)
|
W01TRCA618940 |
[4-(4-アミノフェノキシ)(2-ピリジル)]-N-メチルカルボキサミド
[4-(4-Aminophenoxy)(2-pyridyl)]-N-methylcarboxamide |
284462-37-9 |
250mg |
￥26400 |
2024-03-01 |
購(gòu)入 |
4-(4-アミノフェノキシ)-N-メチル-2-ピリジンカルボキサミド 化學(xué)特性,用途語(yǔ),生産方法
外観
白色～うすい黃色～うすい黃赤色粉末～結(jié)晶
化學(xué)的特性
Light-Brown Solid
使用
Sorafenib intermediate
合成
To a solution of 4-aminophenol (1 g, 9.2 mmol) in DMF (20 mL) was added 1M potassium ier/-butoxide in THF (9.7 mL, 9.7 mmol) at room temperature. After 2h, (4-chloro(2-pyridyl))-N- methyl carboxamide (1.6 g, 9.2 mmol) and potassium carbonate (0.64 g, 4.6 mmol) were added, and then the reaction mixture was heated to 80 °C for 6h. After cooling, the reaction mixture was extracted with ethyl acetate (50 mL). The organic layer was washed with brine (20 mL) and dried over magnesium sulfate. The solvent was removed in vacuo. The residue was purified by column chromatography to afford 4-(4-Aminophenoxy)-N-methylpicolinamide (2.2 g, 80 %) as a light-brown solid.
4-(4-アミノフェノキシ)-N-メチル-2-ピリジンカルボキサミド 上流と下流の製品情報(bào)
原材料
準(zhǔn)備製品
4-(4-アミノフェノキシ)-N-メチル-2-ピリジンカルボキサミド 生産企業(yè)
Global( 425)Suppliers
4-(4-アミノフェノキシ)-N-メチル-2-ピリジンカルボキサミド スペクトルデータ(1HNMR)
284462-37-9(4-(4-アミノフェノキシ)-N-メチル-2-ピリジンカルボキサミド)キーワード:
- 284462-37-9
- 4-(4-aMiNApheNAxy)-N-MethylpicolinaMide
- 4-(4-aMinophenoxy)-N-MethylpicolinaMide oxalate
- N-Methyl-4-(4-aMinophenoxy)pyridine-2-carboxaMide
- 4-(4- aMinophenoxy)-N- Methyl-2- pyridineforMaMide
- 4-(4-Aminophenyloxy)-N-methyl-2-pyridininecarboxamide
- Sorafenib INT2
- 4-(4-aminophenoxy)-N-methylpyridine-2-carboxamide oxalate
- 4-(4-Aminophenoxy)-N-methylpicolinamide
- 4-[[2-(N-Methylcarbamoyl)-4-pyridyl]oxy]anilin
- 4-[[2-(N-Methylcarbamoyl)-4-pyridyl]oxy]aniline
- [4-(4-Aminophenoxy-2-pyridyl)]
- 4-(4-AMino-phenoxy)-pyridine-2-carboxylicacidMethylaMide
- 4-(4-AMinophenoxy)-pyridine-2-carboxylic acid aMide
- 4-(4-Aminophenoxy)-N-methylpicolimide
- [4-(4-Aminophenoxy-2-pyridyl)]-2-methylcarboxamide
- Sorafenib impurity A
- Sorafenib Intermediate
- Sorafenib Related Compound 23
- Sorafenib tosylate INT III
- N-Methyl-4-(4-aminophenoxy)pyridine-2-carboxamide Sorafenib Intermediates II
- 4-(4-Aminophenoxy)-N-methyl-2-pyridinecarboxamide >
- 2-Pyridinecarboxamide, 4-(4-aminophenoxy)-N-methyl-
- 4-(2-N-METHYLCARBOMOYL)-4-PYRIDYLOXY)ANILINE
- 4-(4-Aminophenoxy)-N-methylpicolinamide ISO 9001：2015 REACH
- 4-(4-Aminophenoxy)-N-methylpicolinamide (Sorafenib Impurity)
- 4-(4-Aminophenoxy)-N-methylpyridine-2-carboxamide
- SL-M2
- 4-(4-Aminophenoxy)-N-methyl-2-pyridinecarboxamide (IP2014)
- 4-(4-Aminophenoxy)-N-methyl-2-pyridinecarboxamide
- Sorafenib Aminophenoxy Impurity
- 4-(4-アミノフェノキシ)-N-メチル-2-ピリジンカルボキサミド
- 4-(4-アミノフェノキシ)-N-メチルピコリンアミド
- [4-(4-アミノフェノキシ)(2-ピリジル)]-N-メチルカルボキサミド
- 4-(4-アミノフェノキシ)-N-メチルピリジン-2-カルボキサミド