一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
010-86108875
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List methyl 6-n-pentyl-2-hydroxy-4-oxo-cyclohex-2-ene-1-carboxylate
27871-89-2

methyl 6-n-pentyl-2-hydroxy-4-oxo-cyclohex-2-ene-1-carboxylate synthesis

2synthesis methods
-

Yield:27871-89-2 94 g

Reaction Conditions:

with sodium methylate in methanol; for 3 h;Inert atmosphere;Reflux;

Steps:

B.1 1. Methyl 6-N-Pentyl-2-hydroxy-4-oxo-cyclohex-2-ene-l-carboxylate

[0119] To a stirring solution of sodium methoxide (32.4 g, 0.60 mol) and dimethyl malonate (90 g, 0.68 mol) in 230 mL of anhydrous methanol was added portion wise 75 g (0.48 mol) of 90% 3-nonen-2-one. The reaction mixture was then refluxed for 3 h under N2 and allowed to cool to room temperature. The solvent was distilled under reduced pressure and the residue dissolved in 350 mL of water. The slurry of white crystals and the almost clear solution was extracted thrice with 80 mL of chloroform. The aqueous layer was acidified to pH 4 with concentrated HCl and the white precipitate that formed was allowed to stand overnight prior to filtration. The crystals were dried at 50° C under high vacuum for 5 hours to yield 106.5 g (0.4416 mol) (92%) of methyl 6-n-Pentyl-2-hydroxy-4-oxo-cyclohex-2-ene-l-carboxylate (mp 96-98 C). The product was recrystallized using a mixture of petroleum ethenethyl acetate (9: 1), and gave 94 g of pure methyl 6-n-Pentyl-2-hydroxy-4-oxo-cyclohex-2-ene-l-carboxylate (melting point of 98-100 C).

References:

WO2014/134281,2014,A1 Location in patent:Paragraph 0119

大足县| 子洲县| 云和县| 华宁县| 锦州市| 凤山市| 郴州市| 垫江县| 洛浦县| 大埔县| 通化县| 大港区| 静海县| 西城区| 石柱| 石河子市| 铁力市| 出国| 衡山县| 宿迁市| 北宁市| 响水县| 永德县| 大同县| 曲靖市| 习水县| 晋宁县| 张北县| 平昌县| 来安县| 皮山县| 荔浦县| 延津县| 含山县| 扶沟县| 塔河县| 固镇县| 鄄城县| 阆中市| 江西省| 明星|