Ceramide AP
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- CAS番號(hào).
- 212070-45-6
- 化學(xué)名:
- 別名:
- 英語(yǔ)名:
- Ceramide AP
- 英語(yǔ)別名:
- Ceramide AP;ViableCare Ceramide AP;Water soluble Ceramide VI;Sphingomyelin Impurity 10;Sphingomyelin Impurity 8 (Ceramide VI);Sphingomyelin Impurity 8 (Ceramide VI) (Mixture of Diastereomers);2-hydroxy-N-((2S,3S,4R)-1,3,4-trihydroxyoctadecan-2-yl)octadecanamide;Octadecanamide, N-[(1S,2S,3R)-2,3-dihydroxy-1-(hydroxymethyl)heptadecyl]-2-hydroxy-;Octadecanamide,?N-[(1S,2S,3R)-2,3-dihydroxy-1-(hydroxymethyl)heptadecyl]-2-hydroxy- Octadecanamide,?N-[(1S,2S,3R)-2,3-dihydroxy-1-(hydroxymethyl)heptadecyl]-2-hydroxy-
- CBNumber:
- CB58366512
- 化學(xué)式:
- C36H73NO5
- 分子量:
- 599.97
- MOL File:
- 212070-45-6.mol
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Ceramide AP 物理性質(zhì)
- 沸點(diǎn) :
- 748.3±60.0 °C(Predicted)
- 比重(密度) :
- 0.967±0.06 g/cm3(Predicted)
- 酸解離定數(shù)(Pka):
- 13.26±0.20(Predicted)
- 美容成分審査:
- Ceramide AP (212070-45-6)
- InChIKey:
- BBAFBDLICMHBNU-MFZOPHKMSA-N
- SMILES:
- C(N[C@@H](CO)[C@H](O)[C@H](O)CCCCCCCCCCCCCC)(=O)C(O)CCCCCCCCCCCCCCCC
安全性情報(bào)
- リスクと安全性に関する聲明
- 危険有害性情報(bào)のコード(GHS)
| 絵表示（GHS） |
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| 注意喚起語(yǔ) |
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| 危険有害性情報(bào) |
| コード |
危険有害性情報(bào) |
危険有害性クラス |
區(qū)分 |
注意喚起語(yǔ) |
シンボル |
P コード |
| H302 |
飲み込むと有害 |
急性毒性、経口 |
4 |
警告 |
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P264, P270, P301+P312, P330, P501 |
| H315 |
皮膚刺激 |
皮膚腐食性/刺激性 |
2 |
警告 |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
強(qiáng)い眼刺激 |
眼に対する重篤な損傷性/眼刺激 性 |
2A |
警告 |
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P264, P280, P305+P351+P338,P337+P313P |
| H335 |
呼吸器への刺激のおそれ |
特定標(biāo)的臓器毒性、単回暴露； 気道刺激性 |
3 |
警告 |
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| 注意書(shū)き |
| P280 |
保護(hù)手袋/保護(hù)衣/保護(hù)眼鏡/保護(hù)面を著用するこ と。 |
| P305+P351+P338 |
眼に入った場(chǎng)合：水で數(shù)分間注意深く洗うこと。次にコ ンタクトレンズを著用していて容易に外せる場(chǎng)合は外す こと。その後も洗浄を続けること。 |
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Ceramide AP 価格
| メーカー |
製品番號(hào) |
製品説明 |
CAS番號(hào) |
包裝 |
価格 |
更新時(shí)間 |
購(gòu)入 |
Ceramide AP 化學(xué)特性,用途語(yǔ),生産方法
説明
Ceramide AP (CER [AP]; AP stands for α-hydroxy-N-stearoylphytosphingosine) belongs to a larger group of ceramides that are naturally occurring, long chains of lipids (fats) in the skin. To put it into perspective, the skin’s general composition of ceramides is around 50%; of that, 16% of those ceramides are of the AP variety. CERs are sphingolipids that contain a sphingoid moiety (which can be sphingosine (S), dihydrosphingosine (D), phytosphingosine (P) or 6-hydroxy-sphingosine (H)), linked with a long-chain FFA moiety (which can be nonhydroxy (N), α-hydroxy (A) or ester-linked ω-hydroxy (EO)) through an amide bond. Research indicated that CER [AP], with four hydroxyl groups on its head group, can form super stable membranes through strong hydrogen bonds. It has also been shown to be antiproliferative and proapoptotic in numerous cancer cell types in vitro. Therefore, administration of CER [AP] to the skin might help to restore the barrier function of aged and affected skin[1–2].
利點(diǎn)
Naturally occurring in the skin, Ceramide EOP, also known as ceramide 1, is part of the extracellular matrix that consists mainly of lipids; these waxy molecules are found between the skin cells, resulting in them playing a vital role in keeping the skin surface healthy and hydrated. Over 340 specific species of ceramides were found, and ceramide EOP was the first to show decreased levels of ceramides to weaken the barrier, making skin more vulnerable to external stressors. More specifically, a decline in ceramide AP has been linked to skin conditions such as eczema and psoriasis. Topical application of ceramide APvia skin care formulas can help fill this gap and strengthen the skin’s barrieragainst external stimuli.Generally, ceramideswork best when combined with other replenishing ingredients like fatty acids and cholesterol. These lipid mixtures work in multiple ways to improve skin’s hydration, texture, and suppleness. Ceramides within the skin also play a vital role in maintaining skin health since they signal other processes that keep things orderly.
Ceramide AP 上流と下流の製品情報(bào)
原材料
準(zhǔn)備製品
Ceramide AP 生産企業(yè)
Global( 37)Suppliers
- 212070-45-6
- Octadecanamide, N-[(1S,2S,3R)-2,3-dihydroxy-1-(hydroxymethyl)heptadecyl]-2-hydroxy-
- Ceramide AP
- Water soluble Ceramide VI
- ViableCare Ceramide AP
- Sphingomyelin Impurity 8 (Ceramide VI)
- Octadecanamide,?N-[(1S,2S,3R)-2,3-dihydroxy-1-(hydroxymethyl)heptadecyl]-2-hydroxy- Octadecanamide,?N-[(1S,2S,3R)-2,3-dihydroxy-1-(hydroxymethyl)heptadecyl]-2-hydroxy-
- 2-hydroxy-N-((2S,3S,4R)-1,3,4-trihydroxyoctadecan-2-yl)octadecanamide
- Sphingomyelin Impurity 10
- Sphingomyelin Impurity 8 (Ceramide VI) (Mixture of Diastereomers)