2-Cyano-3-hydroxy-N-(4'-trifluoromethylphenyl)-crotone amide
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- $8 - $1430
- Product name: 2-Cyano-3-hydroxy-N-(4'-trifluoromethylphenyl)-crotone amide
- CAS: 108605-62-5
- MF: C12H9F3N2O2
- MW: 270.21
- EINECS:1308068-626-2
- MDL Number:MFCD00910058
- Synonyms:N-(4-Trifluoromethylphenyl)-2-cyano-3-hydroxycrotonamide, 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-beuteamide, LEF-M;(2Z)-2-[hydroxy-[[4-(trifluoromethyl)phenyl]amino]methylidene]-3-oxo-butanenitrile;2-Cyano-3OH-N-(4-trifluoromethylphenyl) crotonamide-d4;IMp. A (EP) as Hydrochloride: 4-(TrifluoroMethyl)aniline Hydrochloride;TeriflunoMide, A77 1726;2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)crotonamide;2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide;2-Cyano-3-hydroxy-N-(4'-trifluoromethylphenyl)-crotone amide
61 prices
Selected condition：
Brand
- aablocks
- AHH
- AK Scientific
- Ambeed
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth
- Chemenu
- Crysdot
- CSNpharm
- Labseeker
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 5mg
- 250.00mg
- 500mg
- 20mg
- 10mM*1mLinDMSO(Solution)
- 2g
- 50
- 1.00g
- 5.00g
- 10g
- 10mM*1mLinDMSO(Solid+Solvent)
- 1mg
- 10mg
- 0.025g
- 25mg
- 50mg
- 10mM(in1mLDMSO)
- 100mg
- 250mg
- 1g
- 5g
- Manufactureraablocks
- Product numberAA008R6N
- Product descriptionTeriflunomide(Random Configuration) 99+%
- Packaging1mg
- Price$8
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008R6N
- Product descriptionTeriflunomide(Random Configuration) 99+%
- Packaging25mg
- Price$14
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008R6N
- Product descriptionTeriflunomide(Random Configuration) 99+%
- Packaging100mg
- Price$21
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008R6N
- Product descriptionTeriflunomide(Random Configuration) 99+%
- Packaging250mg
- Price$28
- Updated2026-05-28
- Buy
- ManufacturerAHH
- Product numberMT-07007
- Product description2-Cyano-3-OH-N-(4-trifluoromethylphenyl)crotonamide 98%
- Packaging0.025g
- Price$379
- Updated2021-12-16
- Buy
- ManufacturerAHH
- Product numberMT-07007
- Product description2-Cyano-3-OH-N-(4-trifluoromethylphenyl)croton amide 97%
- Packaging0.025g
- Price$379
- Updated2026-05-25
- Buy
- ManufacturerAHH
- Product numberMT-07007
- Product description2-Cyano-3-OH-N-(4-trifluoromethylphenyl)croton amide 97%
- Packaging0.025g
- Price$379
- Updated2026-05-26
- Buy
- ManufacturerAK Scientific
- Product number1709AA
- Product description2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide
- Packaging1g
- Price$500
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number1709AA
- Product description2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide
- Packaging25mg
- Price$107
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number1709AA
- Product description2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide
- Packaging100mg
- Price$163
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number1709AA
- Product description2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide
- Packaging250mg
- Price$230
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA132118
- Product descriptionTeriflunomide(RandomConfiguration) 99+%
- Packaging1g
- Price$222
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA132118
- Product descriptionTeriflunomide(RandomConfiguration) 99+%
- Packaging250mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA132118
- Product descriptionTeriflunomide(RandomConfiguration) 99+%
- Packaging100mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA132118
- Product descriptionTeriflunomide(RandomConfiguration) 99+%
- Packaging25mg
- Price$23
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA132118
- Product descriptionTeriflunomide(RandomConfiguration) 99+%
- Packaging5g
- Price$448
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA008R6N | Teriflunomide(Random Configuration) 99+% | 1mg | $8 | 2026-05-28 | Buy |
| aablocks | AA008R6N | Teriflunomide(Random Configuration) 99+% | 25mg | $14 | 2026-05-28 | Buy |
| aablocks | AA008R6N | Teriflunomide(Random Configuration) 99+% | 100mg | $21 | 2026-05-28 | Buy |
| aablocks | AA008R6N | Teriflunomide(Random Configuration) 99+% | 250mg | $28 | 2026-05-28 | Buy |
| AHH | MT-07007 | 2-Cyano-3-OH-N-(4-trifluoromethylphenyl)crotonamide 98% | 0.025g | $379 | 2021-12-16 | Buy |
| AHH | MT-07007 | 2-Cyano-3-OH-N-(4-trifluoromethylphenyl)croton amide 97% | 0.025g | $379 | 2026-05-25 | Buy |
| AHH | MT-07007 | 2-Cyano-3-OH-N-(4-trifluoromethylphenyl)croton amide 97% | 0.025g | $379 | 2026-05-26 | Buy |
| AK Scientific | 1709AA | 2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide | 1g | $500 | 2021-12-16 | Buy |
| AK Scientific | 1709AA | 2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide | 25mg | $107 | 2021-12-16 | Buy |
| AK Scientific | 1709AA | 2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide | 100mg | $163 | 2021-12-16 | Buy |
| AK Scientific | 1709AA | 2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide | 250mg | $230 | 2021-12-16 | Buy |
| Ambeed | A132118 | Teriflunomide(RandomConfiguration) 99+% | 1g | $222 | 2021-12-16 | Buy |
| Ambeed | A132118 | Teriflunomide(RandomConfiguration) 99+% | 250mg | $90 | 2021-12-16 | Buy |
| Ambeed | A132118 | Teriflunomide(RandomConfiguration) 99+% | 100mg | $60 | 2021-12-16 | Buy |
| Ambeed | A132118 | Teriflunomide(RandomConfiguration) 99+% | 25mg | $23 | 2021-12-16 | Buy |
| Ambeed | A132118 | Teriflunomide(RandomConfiguration) 99+% | 5g | $448 | 2021-12-16 | Buy |
Properties
Melting point :229-232°C
Boiling point :410.8±45.0 °C(Predicted)
Density :1.424±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :Soluble in DMSO (up to 30 mg/ml), or in Ethanol (up to 5 mg/ml with warming).
pka :5.20±0.50(Predicted)
form :Solid
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Major Application :pharmaceutical
InChI :1S/C12H9F3N2O2/c1-7(18)10(6-16)11(19)17-9-4-2-8(3-5-9)12(13,14)15/h2-5,18H,1H3,(H,17,19)/b10-7-
InChIKey :UTNUDOFZCWSZMS-YFHOEESVSA-N
SMILES :O=C(/C(C#N)=C(O)/C)NC1=CC=C(C(F)(F)F)C=C1
Boiling point :410.8±45.0 °C(Predicted)
Density :1.424±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :Soluble in DMSO (up to 30 mg/ml), or in Ethanol (up to 5 mg/ml with warming).
pka :5.20±0.50(Predicted)
form :Solid
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Major Application :pharmaceutical
InChI :1S/C12H9F3N2O2/c1-7(18)10(6-16)11(19)17-9-4-2-8(3-5-9)12(13,14)15/h2-5,18H,1H3,(H,17,19)/b10-7-
InChIKey :UTNUDOFZCWSZMS-YFHOEESVSA-N
SMILES :O=C(/C(C#N)=C(O)/C)NC1=CC=C(C(F)(F)F)C=C1
Safety Information
| Symbol(GHS): |
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| Signal word: | Danger | ||||||||||||||
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Description
Teriflunomide (Aubagio®), also known as A77 1726, is an immunosupressant marketed by Sanofi for the teatment of multiple sclerosis (MS). Teriflunomide is the active metabolite of leflunomide, used for treatment of patients diagnosed with rheumatoid arthritis, and therefore simultaneously can be used as a treatment for rheumatoid arthritis.Teriflunomide acts as an inhibitor of the mitochondrial enzyme dihydrorotate dehydrogenase, inhibiting pyrimidine formation, and resulting in reduced B and T cell proliferation.Related product price
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Suppliers and manufacturers
RongNa Biotechnology Co.,Ltd
Capot Chemical Co.,Ltd.
Henan Tianfu Chemical Co.,Ltd.
Nanjing ChemLin Chemical Industry Co., Ltd.
ATK CHEMICAL COMPANY LIMITED
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Xi'an MC Biotech, Co., Ltd.
Dideu Industries Group Limited
A77 1726
CAS:108605-62-5