3-フェニル-2-プロピン-1-オンジエチルアセタール 化學(xué)特性,用途語(yǔ),生産方法
化學(xué)的特性
CLEAR COLOURLESS TO YELLOW LIQUID
製造方法
To a flask equipped with a 12-in. Vigreux column and distillation head is added 74.0 gm (0.50 mole) of triethyl orthoformate, 51.0 gm (0.50 mole)of phenylacetylene, and 3.0 gm of zinc iodide* catalyst. The flask must first be heated to 135°C before ethanol starts to reflux. The ethanol distillate (26.4 gm) boiling at 65°-88°C is removed over a period of 1 hr while the temperature of the reaction mixture is raised to 200°-210°C. The reaction mixture is cooled and filtered, the precipitate washed with 5 ml of ether and the ether combined with the filtrate is distilled to afford 73-80 gm (72-78%), b.p. 99-100°C (2.0 mm Hg). The IR spectrum showed absorption at 4.5-μ (—C=C—) and 9.0-μ region ( - C — O ).
Synthesis Reference(s)
The Journal of Organic Chemistry, 49, p. 2031, 1984
DOI: 10.1021/jo00185a045
3-フェニル-2-プロピン-1-オンジエチルアセタール 上流と下流の製品情報(bào)
原材料
準(zhǔn)備製品