3-クロロ-β-オキソベンゼンプロパンニトリル 化學(xué)特性,用途語,生産方法
外観
白色～うすい黃色～うすい黃赤色粉末～結(jié)晶
使用
3-Chlorobenzoylacetonitrile has been used in the synthesis biologically active 2-amino-3-benzoylthiophenes and pyrrolopyrimidines that are receptor agonist compounds. 3-Chlorobenzoylacetonitrile and other molecules in its class have also been used in the synthesis of 3-aryl-quinoxaline-2-carbonitrile 1,4-di-N-oxide derivatives as possible anti-tumor treatments.
合成
3-Chlorobenzoylacetonitrile can be synthesized by carbonylation of aryl iodides with Mo(CO)6 in the presence of trimethylsilylacetonitrile and a palladium catalyst.
1
參考文獻(xiàn)
[1]Aldeborgh, H., George, K., Howe, M. et al. Analysis of Small Molecule X-Ray Crystal Structures: Chemical Crystallography with Undergraduate Students in a Teaching Laboratory. J Chem Crystallogr 44, 70–81 (2014).
https://doi.org/10.1007/s10870-013-0485-z
3-クロロ-β-オキソベンゼンプロパンニトリル 上流と下流の製品情報
原材料
準(zhǔn)備製品