N-[4-[1-[2-(6-メチル-2-ピリジニル)エチル]-4-ピペリジニルカルボニル]フェニル]メタンスルホンアミド·2塩酸 価格 もっと(9)

メーカー	製品番號	製品説明	CAS番號	包裝	価格	更新時間	購入
富士フイルム和光純薬株式會社(wako)	W01TOC1808	E-4031二塩酸塩 E-4031 dihydrochloride	113559-13-0	10mg	￥74000	2024-03-01	購入
富士フイルム和光純薬株式會社(wako)	W01TOC1808	E-4031二塩酸塩 E-4031 dihydrochloride	113559-13-0	50mg	￥307000	2024-03-01	購入
Sigma-Aldrich Japan	M5060	≥98% (HPLC), lyophilized powder E-4031 ≥98% (HPLC), lyophilized powder	113559-13-0	0.1mg	￥60100	2024-03-01	購入
Sigma-Aldrich Japan	M5060	≥98% (HPLC), lyophilized powder E-4031 ≥98% (HPLC), lyophilized powder	113559-13-0	0.5mg	￥166000	2024-03-01	購入
Sigma-Aldrich Japan	M5060	≥98% (HPLC), solid E-4031 ≥98% (HPLC), solid	113559-13-0	1mg	￥284000	2024-03-01	購入

N-[4-[1-[2-(6-メチル-2-ピリジニル)エチル]-4-ピペリジニルカルボニル]フェニル]メタンスルホンアミド·2塩酸 化學特性,用途語,生産方法

使用

E-4031 has been used as:

• human ether-a-go-go-related gene (hERG) blocker in human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs)
• IKr blocker in long QT syndrome (LQTS) induced pluripotent stem (iPSCs) embryoid bodies
• IKr blocker in rat ventricular myocytes

生物活性

Selective blocker of hERG K + channels; inhibits the rapid delayed-rectifier K + current (I Kr ). Reversibly prolongs action potential duration in guinea pig papillary muscle and isolated ventricular myocytes, without affecting Na + or Ca 2+ inward currents. Class III antiarrhythmic agent.

Biochem/physiol Actions

E-4031 is a antiarrhythmic drug and belongs to the class III type. It is a methanesulfonanilide compound and is effective in treating arrhythmia and modulates ventricular fibrillation. E-4031 mediates the prolongation of action potential duration (APD) in transgenic long-QT type 1 (LQT1) rabbits. An isoleucine mutation in human ether-a-go-go-related gene (hERG) abolishes its interaction with E-4031.

N-[4-[1-[2-(6-メチル-2-ピリジニル)エチル]-4-ピペリジニルカルボニル]フェニル]メタンスルホンアミド·2塩酸 上流と下流の製品情報

原材料

準備製品

N-[4-[1-[2-(6-メチル-2-ピリジニル)エチル]-4-ピペリジニルカルボニル]フェニル]メタンスルホンアミド·2塩酸 生産企業(yè)

名前	電話番號	電子メール	國籍	製品カタログ	優(yōu)位度
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32998	60
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19935	58
career henan chemical co	+86-0371-86658258	factory@coreychem.com	China	29780	58
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6290	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	38999	58
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +86-15965530500	nickzhang@hangyubiotech.com	China	9937	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850 +86-15355479329	market18@leapchem.com	China	43303	58
Aladdin Scientific		tp@aladdinsci.com	United States	57473	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131885	58

113559-13-0(N-[4-[1-[2-(6-メチル-2-ピリジニル)エチル]-4-ピペリジニルカルボニル]フェニル]メタンスルホンアミド·2塩酸)キーワード:

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• 113559-13-0
• 1-(2-(6-methyl-2-pyridyl)ethyl)-4-(4-methylsulfonylaminobenzoyl)piperidined
• methanesulfonamide,n-(4-((1-(2-(6-methyl-2-pyridinyl)ethyl)-4-piperidinyl)carb
• E-4031
• N-[4-[[1-[2-(6-Methyl-2-pyridinyl)ethyl]-4-piperidinyl]carbonyl]phenyl]methanesulfonamide dihydrochloride
• N-[4-[1-[2-(6-Methyl-2-pyridinyl)ethyl]-4-piperidinylcarbonyl]phenyl]methanesulfonamide·2hydrochloric acid
• E-4031 (hydrochloride)
• N-(4-(1-(2-(6-METHYLPYRIDIN-2-YL)ETHYL)PIPERIDINE-4-CARBONYL)PHENYL)METHANESULFONAMIDE 2HCL
• N-[4-[1-[2-(6-methylpyridin-2-yl)ethyl]piperidine-4-carbonyl]phenyl]methanesulfonamide dihydrochloride
• Inhibitor,anti-arrhythmic,Potassium Channel,E4031,E 4031,KcsA,inhibit,E-4031,hERG
• E4031 diHCl
• Methanesulfonamide, N-[4-[[1-[2-(6-methyl-2-pyridinyl)ethyl]-4-piperidinyl]carbonyl]phenyl]-, hydrochloride (1:2)
• E-4031 dihydrochloride, HERG K+ channel blocker
• N-[4-[1-[2-(6-メチル-2-ピリジニル)エチル]-4-ピペリジニルカルボニル]フェニル]メタンスルホンアミド·2塩酸
• E-4031二塩酸塩
• 抗不整脈薬