Pomalidomide-PEG3-CO2H 価格

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Pomalidomide-PEG3-CO2H 化學(xué)特性,用途語,生産方法

使用

Protein degrader builiding block Pomalidomide-PEG₃-CO₂H enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand and a PEGylated crosslinker with pendant carboxylic acid for reactivity with an amine on the target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant carboxyl group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.

Pomalidomide-PEG3-CO2H 上流と下流の製品情報(bào)

原材料

準(zhǔn)備製品

Pomalidomide-PEG3-CO2H 生産企業(yè)

名前	電話番號(hào)	電子メール	國籍	製品カタログ	優(yōu)位度
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
Shanghai UCHEM Inc.	+862156762820 +86-13564624040	sales@myuchem.com	China	8741	58
Alfa Chemistry	+1-5166625404;	Info@alfa-chemistry.com	United States	20405	58
Nanjing Bicbiotechnology Co., Ltd	+86-2552131256 +86-18251840740	sales@bicbiotech.com	China	5994	58
Jilin Chinese Academy of Sciences-yanshen Technology	+undefined18143011203	info@chemextension.com	China	42056	58
Xian confluore Biological Technology Co., Ltd.	+86-15680926068	1924344760@confluore.cn	China	2997	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58
Suzhou ARTK Medchem Co., Ltd.	+8618118463618	sales1@artkmedchem.com	China	39021	58
Daicel Chiral Technologies (China)CO.,LTD	021-50460086-9 15921403865	han_yajun@dctc.daicel.com	China	7676	65
Bide Pharmatech Ltd.	400-400-164-7117 18317119277	product02@bidepharm.com	China	40000	60

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• 2138440-82-9
• POMALIDOMIDE-PEG 3-CO 2 H
• Pomalidomide-PEG3-CO2H
• 3-[2-[2-[2-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]propanoic acid
• Propanoic acid, 3-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]-
• Pomalidomide-PEG3-CO2H >=95%
• 3-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)ethoxy)propanoic acid
• Thalidomide-NH-PEG3-propionic acid
• Thalidomide-NH-PEG3-C2-COOH
• 3-[2-[2-[2-[[2-(2,6-Dioxo-3-piperidyl)-1,3-dioxo-4-isoindolinyl]amino]ethoxy]ethoxy]ethoxy]propanoic Acid
• Thalidomide-4-NH-PEG3-C2-COOH
• Pomalidomide 4'-PEG3-acid
• 3-{2-[2-(2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}ethoxy)ethoxy]ethoxy}propanoic acid
• 3-[2-[2-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]propanoic acid
• Pomalidomide-PEG₃-CO₂H
• Pomalidomide-PEG3-COOH
• Poma-PEG3-COOH