NH-125
NH-125 物理性質(zhì)
- 融點(diǎn) :
- 88.2-94.9 °C
- 貯蔵溫度 :
- -20°C
- 溶解性:
- DMSO: 20 mg/mL
- 外見 :
- 個(gè)體
- 色:
- ホワイトからオフホワイト
- InChI:
- 1S/C27H45N2.HI/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-19-22-28-23-24-29(26(28)2)25-27-20-17-16-18-21-27;/h16-18,20-21,23-24H,3-15,19,22,25H2,1-2H3;1H/q+1;/p-1
- InChIKey:
- RVWOHCBHAGBLLT-UHFFFAOYSA-M
- SMILES:
- [I-].CCCCCCCCCCCCCCCC[n+]1ccn(Cc2ccccc2)c1C
| メーカー |
製品番號 |
製品説明 |
CAS番號 |
包裝 |
価格 |
更新時(shí)間 |
購入 |
|
富士フイルム和光純薬株式會社(wako)
|
W01CAY10011250 |
NH125 |
278603-08-0 |
1mg |
￥11200 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式會社(wako)
|
W01TOC3439 |
NH 125 |
278603-08-0 |
50mg |
￥272000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式會社(wako)
|
W01CAY10011250 |
NH125 |
278603-08-0 |
5mg |
￥33000 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
N2162 |
≥98% (HPLC), solid
NH125 ≥98% (HPLC), solid |
278603-08-0 |
5mg |
￥62400 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式會社(wako)
|
W01TOC3439 |
NH 125 |
278603-08-0 |
10mg |
￥66000 |
2024-03-01 |
購入 |
NH-125 化學(xué)特性,用途語,生産方法
使用
NH125 is an inhibitor of multiple kinases. It kills methicillin-resistant Staphylococcus.
生物活性
Histidine protein kinase and eukaryotic elongation factor 2 (eEF-2) kinase (CaMK III) inhibitor (IC 50 = 60 nM) that displays 125-fold, > 1300-fold and > 1500-fold selectivity over PKC, PKA and CaMK II respectively. Exhibits anticancer activity in a variety of malignant cell lines (IC 50 values are 0.7 - 4.8 μ M) and blocks G 1 /S cell cycle progression. Also is an effective antibacterial agent in vitro (IC 50 = 6.6 μ M) and in vivo .
Biochem/physiol Actions
NH125 exhibits anti-proliferation activity against many cancer cells. It also exhibits antibacterial effects by inhibiting bacterial histidine protein kinase.
NH-125 上流と下流の製品情報(bào)
原材料
準(zhǔn)備製品
NH-125 生産企業(yè)
Global( 82)Suppliers
278603-08-0(NH-125)キーワード:
- 278603-08-0
- 1-Hexadecyl-2-methyl-3-(phenylmethyl)-1H-imidazoliumiodide
- eEF-2 Kinase Inhibitor, NH125
- eEF-2 Kinase Inhibitor, NH125 - CAS 278603-08-0 - Calbiochem
- EEF-2 KINASE INHIBITOR
- NH125 USP/EP/BP
- 3-Benzyl-1-hexadecyl-2-methyl-1H-imidazol-3-ium iodide
- NH 125,Calmodulin-dependent protein kinases,NH-125,Calmodulin-dependent kinases,NH125,Inhibitor,Autophagy,inhibit,Fungal,Virus Protease,Bacterial,CaMK
- NH 125, CaMK III inhibitor
- NH125, 10 mM in DMSO
- NH125 ，S7436
- 3-benzyl-1-decahexalkaneyl-2-methyl-1H-imidazole-3-iodo
- 3-ベンジル-1-ヘキサデシル-2-メチル-1H-イミダゾール-3-イウム?ヨージド
- 1-ベンジル-3-セチル-2-メチル-3H-イミダゾール-1-イウム?ヨージド
- NH-125
- 1-ベンジル-2-メチル-3-ヘキサデシル-3H-イミダゾール-1-イウム?ヨージド
- 1-ヘキサデシル-2-メチル-3-ベンジル-1H-イミダゾール-3-イウム?ヨージド