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?????? ??? ???
?? ??:
292634-27-6
???:
??????
???(??):
??????
???:
Dianicline
???(??):
Dianicline;Dianicline dihydrochloride;(5aS,8S,10aR)-5a,6,9,10-Tetrahydro-7H,11H-8,10a-methanopyrido[2',3':5,6]pyrano[2,3-d]azepine;7H,11H-8,10a-Methanopyrido[2',3':5,6]pyrano[2,3-d]azepine, 5a,6,9,10-tetrahydro-, (5aS,8S,10aR)-
CBNumber:
CB01508596
???:
C13H16N2O
??? ??:
216.28
MOL ??:
292634-27-6.mol

?????? ??

?? ?
350.9±42.0 °C(Predicted)
??
1.26±0.1 g/cm3(Predicted)
?? ??
Store at -20°C
???
DMSO: 25 mg/mL (86.45 mM)
??? ??
Solid
?? ?? (pKa)
9.04±0.20(Predicted)
??
White to off-white

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Dianicline is an α4β2 nicotinic acetylcholine receptor partial agonist that may have therapeutic potential in the clinical management of smoking cessation. Dianicline is able to increase dopamine release in the nucleus accumbens shell in rats.

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