??????-d4
|
|
??????-d4 ??
- ???
- 242-244°C
- ??
- 1.511±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
- ?? ??
- -20°C Freezer
- ???
- DMSO(?? ???), ???(?? ???, ?????)
- ?? ?? (pKa)
- 8.063±0.20(predicted)
- ??? ??
- ??
- ??? ??
- ??? ??
- ??
- ???? ?????
??
??????-d4 C??? ??, ??, ??
??
Aprepitant-d4 is a labeled analogue of Aprepitant (A729800), A novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Aprepitant-d4 is a potential treatment for chemotherapy induced nausea and vomiting.??????-d4 ?? ?? ? ???
???
?? ??
??????-d4 ?? ??
???( 40)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19936 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 |
jkinfo@jkchemical.com | China | 96815 | 76 |
| Shanghai TaoSu Biochemical Technology Co., Ltd. | 021-33632979 |
info@tsbiochem.com | China | 8065 | 58 |
| Cato Research Chemicals Inc. | 020-81960175 |
min.he@cato-chem.com | China | 1955 | 55 |
| Quality Control Solutions Ltd. | 0755-66853366 13670046396 |
orders@qcsrm.com | China | 18190 | 56 |
| Shenzhen SUNGENING Bio-Medical Co., Ltd. | 0755-28967200 13631290199 |
wxf@sungening.com | China | 9629 | 60 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 |
sales@rrkchem.com | China | 57422 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 |
sales@chemegen.com | China | 11218 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 |
marketing1@energy-chemical.com | China | 45000 | 58 |
| Foshan Treasure Biotechnology Co., Ltd | 0757-85921206 18520245316 |
2329783215@qq.com | China | 12661 | 58 |