ChemicalBook >?? ???? >?? ??>?? ??>1-(o-???-α-????)????

1-(o-???-α-????)????

1-(o-???-α-????)???? ??? ???

?? ??:: 109036-15-9

???:: 1-(o-???-α-????)????

???(??):: 1-(o-???-α-????)????

???:: 1-(o-Chloro-α-phenylbenzyl)piperazine

???(??):: 1-[(2-Chlorophenyl)phenylMethyl]piperazine;1-(o-Chloro-αCetirizine SM impurity;Cinnarizine EP Impurity;-phenylbenzyl)piperazine;Cinnarizine SM Impurity 3;Levocetirizine Impurity 5;Cinnarizine EP Impurity 3;Cetirizine SM impurity 3 HCl;Cinnarizine EP Impurity 3 HCl

CBNumber:: CB02621269

???:: C17H19ClN2

??? ??:: 286.8

MOL ??:: 109036-15-9.mol

?? ?? 29

1-(o-???-α-????)???? ??

?? ?: 154 °C(Press: 0.01 Torr)

??: 1.158±0.06 g/cm3(Predicted)

?? ??: Refrigerator, under inert atmosphere

???: ?????(?? ???), ???(?? ???)

??? ??: ??

?? ?? (pKa): 8.98±0.10(Predicted)

??: ????? ?? ?????

?? ? ?? ??
?? ? ???? ?? (GHS)

????(GHS):

?? ?:

Warning

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	P- ??
H302	??? ???	?? ?? ?? - ??	?? 4	??	P264, P270, P301+P312, P330, P501
H315	??? ??? ???	????? ?? ?????	?? 2	??	P264, P280, P302+P352, P321,P332+P313, P362
H319	?? ?? ??? ???	?? ? ?? ?? ??? ??	?? 2A	??	P264, P280, P305+P351+P338,P337+P313P
H335	?? ???? ??? ? ??	?? ???? ?? - 1? ??;???? ??	?? 3	??

??????:

P264	?? ??? ?? ??? ????.
P264	?? ??? ?? ??? ????.
P270	? ??? ??? ??? ???, ???? ???? ???.
P280	????/???/???/?????? ?????.
P301+P312	??? ???? ??? ????(??)? ??? ????.
P302+P352	??? ??? ??? ?? ????.
P305+P351+P338	?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P321	(…) ??? ???.
P330	?? ?????.
P332+P313	?? ??? ??? ???? ??· ??? ????.
P362	??? ??? ?? ?? ?? ?????
P501	...? ??? / ??? ?? ???.

1-(o-???-α-????)???? C??? ??, ??, ??

??

1-[(2-Chlorophenyl)phenylmethyl]piperazine is a novel compound derived from the previously reported N-type calcium channel blocker NP118809 (1-(4-benzhydrylpiperazin-1-yl)-3,3-diphenylpropan-1-one).

1-(o-???-α-????)???? ?? ?? ? ???

???

?? ??

1-(o-???-α-????)???? ?? ??

???( 29)?? ??

???	??	???	??	?? ?	??
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1-(o-???-α-????)???? ?? ??:

Levocetirizine Impurity 4 Levocetirizine amide impurity HCl (R)-1-[(4-Chlorophenyl)phenylmethyl]piperazine

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