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3-(????????)-1,2-?????

3-(????????)-1,2-?????
3-(????????)-1,2-????? ??? ???
?? ??:
6452-57-9
???:
3-(????????)-1,2-?????
???(??):
3-(????????)-1,2-?????
???:
3-(ISOPROPYLAMINO)-1,2-PROPANEDIOL
???(??):
3-(isopropylamino)propane-1,2-diol;AURORA KA-6876;Metoprolol Impurity N;Metoprolol Impurity 43;3-(Isopropylamino)-1,2-propane;Metoprolol Succinate Impurity N;3-Isopropylamine-1,2-propanediol;Metoprolol tartrate EP impurity N;3-(ISOPROPYLAMINO)-1,2-PROPANEDIOL;Metoprolol Succinate EP Impurity N
CBNumber:
CB0268451
???:
C6H15NO2
??? ??:
133.19
MOL ??:
6452-57-9.mol
MSDS ??:
SDS

3-(????????)-1,2-????? ??

?? ?
254.4±25.0 °C(Predicted)
??
1.007±0.06 g/cm3(Predicted)
?? ??
Room Temperature
???
?????, DMSO(?? ???), ???(?? ???)
??? ??
??
??? ??
??? ??
?? ?? (pKa)
14.04±0.20(Predicted)
??
????? ?? ???
?? ??
??? ??
InChI
1S/C6H15NO2/c1-5(2)7-3-6(9)4-8/h5-9H,3-4H2,1-2H3
InChIKey
YKBZGEJJKPNRSI-UHFFFAOYSA-N
SMILES
OCC(O)CNC(C)C
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
WGK ?? WGK 3
???? ??? 10 - Combustible liquids
????(GHS): Corrosion (GHS05)Exclamation Mark (GHS07)
?? ?: Danger
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H314 ??? ?? ??? ?? ??? ??? ????? ?? ????? ?? 1A, B, C ?? P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H318 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 1 ?? P280, P305+P351+P338, P310
H332 ???? ??? ?? ?? ?? ?? ?? 4 ?? P261, P271, P304+P340, P312
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ??
H412 ??? ??? ?? ????? ??? ?? ????? ?? - ?? ?? 3 P273, P501
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P273 ???? ???? ???.
P280 ????/???/???/?????? ?????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P310 ?? ????(??)? ??? ????. ???? ?? ????(??)? ??? ????.

3-(????????)-1,2-????? C??? ??, ??, ??

??

3-Isopropylamino-1,2-propanediol (Metoprolol EP Impurity N) is a versatile organic building block, used in different chemical synthesis. It is used in the preparation of heterocyclic propanolamines, which are shown to have β-adrenergic antagonist activity.

3-(????????)-1,2-????? ?? ?? ? ???

???

?? ??


3-(????????)-1,2-????? ?? ??

???( 111)?? ??
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3-(????????)-1,2-????? ?? ??:

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