5-??-??

5-??-?? ??? ???

?? ??:: 641-85-0

???:: 5-??-??

???(??):: 5-??-??

???:: 5-ALPHA-PREGNANE

???(??):: Pregnane;5α-Pregnane;ALLOPREGNANE;5ALPHA-PREGNAN;Pregnane, (5α)-;5-ALPHA-PREGNANE;Pregnane, (5alpha)-;5α(H)-Pregnane in isooctane

CBNumber:: CB0297589

???:: C21H36

??? ??:: 288.51

MOL ??:: 641-85-0.mol

?? ?? 6

5-??-?? ??

???: 84-85°

??: D19 +18.4° (c = 1.69 in chloroform)

?? ?: 365.73°C (rough estimate)

??: 0.9415 (estimate)

???: 1.7640 (estimate)

CAS ??????: 641-85-0

?? ? ?? ??
?? ? ???? ?? (GHS)

??? ??	Xi
?? ???? ??	36/37/38
?????	26-36

????(GHS):

?? ?:

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	?? ??	P- ??
H413	??? ??? ?? ????? ??? ??? ??	?? ????? ?? - ??	?? 4

??????:

5-??-?? C??? ??, ??, ??

Purification Methods

Recrystallise 5-pregnane several times from Me2CO. The melting point is lowered (e.g. to 50-71o) if it is contaminated with the 5-isomer. [Butenandt et al. Chem Ber 6 4 2529 1931, Steiger & Reichstein Helv Chim Acta 21 161 1938, Beilstein 5 III 1120, 1121, 1125.]

5-??-?? ?? ?? ? ???

???

?? ??

5-??-?? ?? ??

???( 6)?? ??

???	??	???	??	?? ?	??
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5-??-?? ?? ??:

Allopregnanolone 5-ALPHA-PREGNAN-3-ALPHA, 20-ALPHA-DIOL HECOGENIN ACETATE TOMATINE CHOLESTANOL ACETATE 17,21-dihydroxy-5alpha-pregnane-3,11,20-trione 21-acetate 3-beta,17-alpha-dihydroxy-5-alpha-pregnan-20-one ALLOTETRAHYDROCORTISOL 21-HYDROXYALLOPREGNANOLONE ALLOTETRAHYDRO S ALLOPREGNANOLONE ACETATE ALLOTETRAHYDROCORTICOSTERONE TIGOGENIN ACETATE 6-KETOCHOLESTANOL 11-KETOTIGOGENIN 5-ALPHA-CHOLANIC ACID-3,6-DIONE ROCKOGENIN 5-ALPHA-PREGNAN-3-BETA, 20-ALPHA-DIOL 3-ACETATE

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