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2-HYDROXYSACLOFEN

2-HYDROXYSACLOFEN ??? ???
?? ??:
117354-64-0
???:
2-HYDROXYSACLOFEN
???(??):
2-Oh-saclofen;HYDROXYSACLOFEN;2-HYDROXYSACLOFEN;2-HYDROXYSACLOFEN, >99%;2-Hydroxysaclofen solid;2 Hydroxysaclofen,2Hydroxysaclofen;2-Hydroxysaclofen >=98% (TLC), solid;2-HYDROXYSACLOFEN ISO 9001:2015 REACH;2-HYDROXYSACLOFEN GABA(B) RECEPTOR ANTA;3-amino-2-(4-chlorophenyl)-2-hydroxy-*propanesulf
CBNumber:
CB0299578
???:
C9H12ClNO4S
??? ??:
265.71
MOL ??:
117354-64-0.mol
MSDS ??:
SDS

2-HYDROXYSACLOFEN ??

???
267-269 °C
RTECS ??
DA0359200
?? ??
2-8°C
???
H2O: 1 mg/mL
??? ??
??
??? ??
??? ??
??
???
???
1mg/ml? ?? ?????. DMSO, 0.1M HCl ? ????? ?????.
InChI
1S/C9H12ClNO4S/c10-8-3-1-7(2-4-8)9(12,5-11)6-16(13,14)15/h1-4,12H,5-6,11H2,(H,13,14,15)
InChIKey
WBSMZVIMANOCNX-UHFFFAOYSA-N
SMILES
NCC(O)(CS(O)(=O)=O)c1ccc(Cl)cc1
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? C
?? ???? ?? 34
????? 26-27-36/37/39-45
????(UN No.) UN 1759 8/PG 3
WGK ?? 3
?? ?? 8
???? ??? 8A - Combustible corrosive hazardous materials
Hazard Classifications Skin Corr. 1B
????(GHS): Corrosion (GHS05)
?? ?: Danger
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H314 ??? ?? ??? ?? ??? ??? ????? ?? ????? ?? 1A, B, C ?? P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
??????:
P280 ????/???/???/?????? ?????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P310 ?? ????(??)? ??? ????. ???? ?? ????(??)? ??? ????.

2-HYDROXYSACLOFEN C??? ??, ??, ??

??

2-Hydroxysaclofen is a GABA-B receptor antagonist in the ventral tegmental area and may play a role in the mechanisms of cocaine usage. Affects specific acute nicotine responses in mice, abolishing hypolocomotion and increasing antinociception.

???? ??

Selective antagonist at GABA B receptors.

2-HYDROXYSACLOFEN ?? ?? ? ???

???

?? ??


2-HYDROXYSACLOFEN ?? ??

???( 51)?? ??
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2-HYDROXYSACLOFEN ?? ??:

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