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2-(2-???-5-??????)???

2-(2-???-5-??????)???
2-(2-???-5-??????)??? ??? ???
?? ??:
1563-56-0
???:
2-(2-???-5-??????)???
???(??):
2-(2-???-5-??????)???
???:
2-(2-AMINO-5-BROMOBENZOYL) PYRIDINE
???(??):
C2HyBnN2O;Bromazepam Impurity A;Tocopherol Impurity 30;Bromazepam EP Impurity A;2-(2-AMINO-5-BROMOBENZOYL);2-amino-5-bromobenzoylpyridine;2-(2-Ao-5-bromobenzoyl) pyridine;2-(2-AMino-5-BroMobenzoyl) Pyridin;2-(5-Bromo-2-aminobenzoyl)pyridine;2-(2-AMINO-5-BROMOBENZOYL) PYRIDINE
CBNumber:
CB0371601
???:
C12H9BrN2O
??? ??:
277.12
MOL ??:
1563-56-0.mol

2-(2-???-5-??????)??? ??

???
98-100℃
?? ?
451℃
??
1.546
???
227℃
?? ??
Keep in dark place,Inert atmosphere,Room temperature
???
DMSO(?? ???), ???(?? ???)
??? ??
??
??? ??
??? ??
?? ?? (pKa)
2.66±0.10(Predicted)
??
?? ????? ?????
InChI
InChI=1S/C12H9BrN2O/c13-8-4-5-10(14)9(7-8)12(16)11-3-1-2-6-15-11/h1-7H,14H2
InChIKey
KHVZPFKJBLTYCC-UHFFFAOYSA-N
SMILES
C(C1=CC(Br)=CC=C1N)(C1=NC=CC=C1)=O
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
HS ?? 2933399990
????(GHS): Exclamation Mark (GHS07)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? P264, P270, P301+P312, P330, P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ??
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

2-(2-???-5-??????)??? C??? ??, ??, ??

??? ??

Yellow Solid

??

2-(2-Amino-5-bromobenzoyl)pyridine is used as an intermediate in the preparation of Bromazepam.

???? ??

2-(2-AMINO-5-BROMOBENZOYL) PYRIDINE (2ABBP) has been shown to have anti-inflammatory properties in rat liver microsomes and cell culture experiments. The mechanism of action may involve inhibition of cyclooxygenase enzymes, which are involved in prostaglandin synthesis. 2ABBP also binds to human serum albumin and chaperones, proteins that bind other proteins or small molecules.

2-(2-???-5-??????)??? ?? ?? ? ???

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2-(2-???-5-??????)??? ?? ??

???( 219)?? ??
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