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2-HYDROXYHEXADECANOIC ACID

2-HYDROXYHEXADECANOIC ACID ??? ???
?? ??:
764-67-0
???:
2-HYDROXYHEXADECANOIC ACID
???(??):
Hydroxypalmiticacid;2-HYDROXY C16:0 ACID;2-hydroxypalmiticaci;2-HYDROXYPALMITIC ACID;HYDROXYPALMITIC ACID, 2-;2-HydroxypalmiticAcid>dl-A-hydroxypalmitic acid;2-HYDROXYHEXADECANOIC ACID;alpha-Hydroxypalmitic acid;Hexadecanoic acid, 2-hydroxy-
CBNumber:
CB0408835
???:
C16H32O3
??? ??:
272.42
MOL ??:
764-67-0.mol
MSDS ??:
SDS

2-HYDROXYHEXADECANOIC ACID ??

???
86 °C
?? ?
405.5±18.0 °C(Predicted)
??
0.955±0.06 g/cm3(Predicted)
?? ??
2-8°C
???
very faint turbidity in Methanol
??? ??
powder to crystal
?? ?? (pKa)
3.86±0.21(Predicted)
??
???? ?? ??
?? ??
Consistent with structure
InChI
1S/C16H32O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15(17)16(18)19/h15,17H,2-14H2,1H3,(H,18,19)
InChIKey
JGHSBPIZNUXPLA-UHFFFAOYSA-N
SMILES
CCCCCCCCCCCCCCC(O)C(O)=O
LogP
6.210 (est)
CAS ??????
764-67-0(CAS DataBase Reference)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
WGK ?? 3
HS ?? 2918.19.9000
???? ??? 11 - Combustible Solids
???? ?? KE-20786
????(GHS): Exclamation Mark (GHS07)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
??????:
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P280 ????/???/???/?????? ?????.
NFPA 704
0
2 0

2-HYDROXYHEXADECANOIC ACID C??? ??, ??, ??

??

2-Hydroxyhexadecanoic Acid is used in the investigation of role of hypoxia in mechanism of action of elisidepsin which reduces drug efficiency by inhibiting hydroxylation and altering structure of lipid rafts in human SKBR-3, MCF-7, MDA-MB-453 cell lines. Also used in the studies on the antiviral activity of hydroxy fatty acids.

??

ChEBI: A 2-hydroxy fatty acid comprising a C16 straight chain carrying a hydroxy substituent at position 2.

Biochem/physiol Actions

2-Hydroxyhexadecanoic acid (2OH-HDA) is used as a representative of the saturated long-chain hydroxyl fatty acids group, members of which have potential roles in anti-inflammatory action, neuroprotection, and bactericide and anti-cancer defense.

2-HYDROXYHEXADECANOIC ACID ?? ?? ? ???

???

?? ??


2-HYDROXYHEXADECANOIC ACID ?? ??

???( 123)?? ??
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