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5-???-2-????????

5-???-2-????????
5-???-2-???????? ??? ???
?? ??:
16588-24-2
???:
5-???-2-????????
???(??):
5-???-2-????????
???:
4-Bromo-1-chloro-2-nitrobenzene
???(??):
4-BROMO-1-CHLORO-2-NITROBENZENE;5-BROMO-2-CHLORONITROBENZENE;2-chloro-5-bromonitrobenzene;1-Bromo-4-chloro-3-nitrobenzene;5-Bromo-1-chloro-2-nitrobenzene;Benzene, 4-broMo-1-chloro-2-nitro-;4-Bromo-1-chloro-2-nitrobenzene >(dimethylamino)ethyl]-,[s-(r*,s*)]-(9ci)
CBNumber:
CB0414522
???:
C6H3BrClNO2
??? ??:
236.45
MOL ??:
16588-24-2.mol

5-???-2-???????? ??

???
0°C
?? ?
0°C
??
2.035 g/cm3(Temp: 16 °C)
???
0°C
?? ??
Sealed in dry,Room Temperature
???
???? ???
??? ??
powder to crystal
??
???? ?? ???
?? ??(λmax)
313nm(H2O)(lit.)
CAS ??????
16588-24-2
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi
?? ?? IRRITANT
HS ?? 2904990090
????(GHS): Exclamation Mark (GHS07)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
??????:
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

5-???-2-???????? C??? ??, ??, ??

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4-Bromo-1-chloro-2-nitrobenzene (5-Bromo-2-chloronitrobenzene) is a pharmaceutical intermediate compound used in the preparation of vismodegib, a molecular inhibitor of the Hedgehog signalling pathway approved for the treatment of metastatic and locally advanced basal cell carcinoma (BCC).

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