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NOR-3

NOR-3 ??? ???
?? ??:
138472-01-2
???:
NOR-3
???(??):
NOR-3;FK409;4-ETHYL2-E-(HYDROXYIMINO)-5-NITRO-3E-HEXENAMIDE;(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide;3-Hexenamide, 4-ethyl-2-(hydroxyimino)-5-nitro-, (2E,3E)-;(+/-)-(E)-ETHYL-2-[(E)-HYDROXYIMINO]-5-NITRO-3-HEXENEAMIDE;(+/-)-(E)-4-ETHYL-2-[(E)-HYDROXYIMINO]-5-NITRO-3-HEXENAMIDE;(+/-)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexeneamide (NOR 3)
CBNumber:
CB0484659
???:
C8H13N3O4
??? ??:
215.21
MOL ??:
138472-01-2.mol
MSDS ??:
SDS

NOR-3 ??

?? ??
−20°C
???
DMF: >34 mg/ml; DMSO: >20 mg/ml; Ethanol: >36 mg/ml; PBS pH 7.2: >2.2 mg/ml
??? ??
?? ?? ???? ??? ??.
InChI
1S/C8H13N3O4/c1-3-6(5(2)11(14)15)4-7(10-13)8(9)12/h4-5,13H,3H2,1-2H3,(H2,9,12)/b6-4+,10-7+
InChIKey
MZAGXDHQGXUDDX-AGLLBGTNSA-N
SMILES
CC\C(=C/C(=N\O)C(N)=O)C(C)[N+]([O-])=O
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? T
?? ???? ?? 25
????? 45
????(UN No.) UN 2811 6.1 / PGIII
WGK ?? 3
???? ??? 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Acute Tox. 3 Oral
????(GHS): Skull and Crossbones (GHS06)
?? ?: Danger
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H301 ??? ??? ?? ?? ?? - ?? ?? 3 ?? P264, P270, P301+P310, P321, P330,P405, P501
??????:
P301+P310 ???? ?? ????(??)? ??? ????.
NFPA 704
0
2 0

NOR-3 C??? ??, ??, ??

??

FK-409 is a NO donor. It liberates NO in a time-dependent manner with a half-life of approximately 40 minutes in phosphate buffer (pH 7.4) at 37°C. The IC50 for the inhibition of platelet aggregation is 4.9 μM.

NOR-3 ?? ?? ? ???

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NOR-3 ?? ??:

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