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SWAINSONINE

SWAINSONINE ??? ???

?? ??:: 72741-87-8

???:: SWAINSONINE

???(??):: 8AR)-1;SwainMoia;Tridolgosir;SWAINSONINE;D-Swainsonine;(-)-Swainsonine;SWAINSONINE 98+%;(-)-D-Swainsonine;Swainsonine min. 99%;swainsonine synthetic

CBNumber:: CB0484750

???:: C8H15NO3

??? ??:: 173.21

MOL ??:: 72741-87-8.mol

MSDS ??:: SDS

?? ?? 205

SWAINSONINE ??

???: 148-149°C

?? ?: 353.3±21.0 °C(Predicted)

??: 1.38±0.1 g/cm3 (20 ºC 760 Torr)

?? ??: -20°C

???: H2O: ???1mg/mL

?? ?? (pKa): 14.01±0.60(Predicted)

??? ??: ????? ??

??: ???? ??? ?????

???? ??: synthetic

???: ?? 50mM?? ???

BRN: 4175740

???: ??? ?? ?????? 1? ?? ??????. DMSO, ??? ?? ???? ??? ??? -20°C?? ?? 3?? ?? ??? ? ????.

InChI: 1S/C8H15NO3/c10-5-2-1-3-9-4-6(11)8(12)7(5)9/h5-8,10-12H,1-4H2/t5-,6-,7,8-/m1/s1

InChIKey: FXUAIOOAOAVCGD-DCDLSZRSSA-N

SMILES: O[C@@H]1CCCN2C[C@@H](O)[C@@H](O)C12

CAS ??????: 72741-87-8

?? ? ?? ??
?? ? ???? ?? (GHS)

??? ??	Xn
?? ???? ??	20/21/22
?????	36
WGK ??	3
RTECS ??	NM2408666
HS ??	29339900
???? ???	11 - Combustible Solids

????(GHS):

?? ?:

Warning

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	P- ??
H302	??? ???	?? ?? ?? - ??	?? 4	??	P264, P270, P301+P312, P330, P501
H312	??? ???? ???	?? ?? ?? - ??	?? 4	??	P280,P302+P352, P312, P322, P363,P501
H332	???? ???	?? ?? ?? ??	?? 4	??	P261, P271, P304+P340, P312

??????:

P280

????/???/???/?????? ?????.

NFPA 704

	0
3		0

SWAINSONINE C??? ??, ??, ??

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White Crystalline Solid

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Swainsonia canescens yields this simple alkaloid.

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ChEBI: An indolizidine alkaloid isolated from the plant Swainsona canescens with three hydroxy substituents at positions 1, 2 and 8.

?? ??

Swainsonine is produced by endophytes, plant and insect pathogens. It is synthesized from the pipecolic acid and mevalonic acid. Swainsonine is a water-soluble indole alkaloid.

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Inhibitor of α -mannosidase II which inhibits glycoprotein processing. Displays anticancer and immune modulatory properties.

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SWAINSONINE ?? ??:

1-???-N,N,N-??????????, ???? CONDURITOL B EPOXIDE (-)-Gossypol Mitomycin C C2 CERAMIDE 1-Hexanol 1-Octacosanol SWAINSONINE(P) 1,2-di-epi-swainsonine swainsonine N-oxide L-(+)-SWAINSONINE 1,2-ISOPROPYLIDENE SWAINSONINE SWAINSONINE-6,7-3H 6,7-DIHYDROXYSWAINSONINE SWAINSONINE (1S,2R,8R,8AR)-1,2,8-TRIACETOXY-OCTAHYDRO-5-OXYINDOLIZINE

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