Paricalcitol
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Paricalcitol ??
- ?? ?
- 564.8±50.0 °C(Predicted)
- ??
- 1.121±0.06 g/cm3(Predicted)
- ???
- 14℃
- ?? ??
- Store at -20°C,unstable in solution, ready to use.
- ???
- DMSO : 100 mg/mL (240.02 mM; Need ultrasonic)Ethanol : 12.5 mg/mL (30.00 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
- ?? ?? (pKa)
- 14.34±0.40(Predicted)
- ??? ??
- Solid
- ??
- White to off-white
- Henry's Law Constant
- 2.6×101 mol/(m3Pa) at 25℃, HSDB (2015)
- InChIKey
- BPKAHTKRCLCHEA-UBFJEZKGSA-N
- SMILES
- C[C@]12CCC/C(=C\C=C3C[C@@H](O)C[C@H](O)C3)/[C@]1([H])CC[C@]2([H])[C@H](C)/C=C/[C@H](C)C(O)(C)C |&1:1,10,13,16,20,22,26,r|
- CAS ??????
- 131918-61-1(CAS DataBase Reference)
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- ?? ? ???? ?? (GHS)
| ????(UN No.) | UN1170 - class 3 - PG 2 - Ethanol, solution | ||
|---|---|---|---|
| WGK ?? | WGK 3 | ||
| HS ?? | 2936299055 | ||
| ???? ??? | 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials |
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| Hazard Classifications | Acute Tox. 2 Inhalation Acute Tox. 3 Dermal Acute Tox. 3 Oral STOT RE 1 Oral |
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| ?? ?? ??? | 131918-61-1(Hazardous Substances Data) |
Paricalcitol C??? ??, ??, ??
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Paricalcitol was launched as Zemplar in the US for the prevention and treatment of secondary hyperthyroidism associated with chronic renal failure. Paricalcitol is a synthetic vitamin D2, namely a novel 1-alpha-hydroxy-19-noranalogue in which the ring A exocyclic methylene group, typical of all vitamin D systems, has been replaced by two hydrogen atoms. Paricalcitol is the first vitamin D analogue marketed for this indication. In patients with chronic renal failure, Paricalcitol appreciably reduced levels of parathyroid hormone (PTH) without a significant difference in the incidence rate for hypercalcemia or hyperphosphatemia when compared with placebo.??? ??
White Solid??
1,25-Dihydroxy vitamin D2 is a potent agonist of the vitamin D receptor. Paricalcitol is a synthetic 1,25-dihydroxy vitamin D2 analog. As vitamin D deficiency, associated with chronic kidney disease, leads to an increase in parathyroid hormone (secondary hyperparathyroidism), paricalcitol is used in renal patients to block parathyroid hormone overproduction. Vitamin D deficiency is also a risk factor in cancer, cardiovascular disease, hypertension, and diabetes, and paricalcitol may have applications in those contexts as well.Paricalcitol ?? ?? ? ???
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Paricalcitol ?? ??
???( 307)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| airuikechemical co., ltd. | +86-18353166132 |
sales02@airuikechemical.com | China | 983 | 58 |
| HangZhou RunYan Pharma Technology Co.,LTD. | +86-18882027439 |
sales2@runyanpharma.com | China | 302 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 |
sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 |
info@dakenam.com | China | 14026 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21585 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3619 | 58 |
| Biochempartner | 0086-13720134139 |
candy@biochempartner.com | CHINA | 965 | 58 |
| BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19936 | 58 |
| CONIER CHEM AND PHARMA LIMITED | |
sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 |
factory@coreychem.com | China | 29792 | 58 |
Paricalcitol ?? ??:
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Paricalcitol Solution
Paricalcitol
1(ALPHA) 25-DIHYDROXYVITAMIN D2*