ChemicalBook >?? ???? >?? ??>?? ??>??? ?? ????>METHYL ARACHIDONATE

METHYL ARACHIDONATE

METHYL ARACHIDONATE ??? ???

?? ??:: 2566-89-4

???:: METHYL ARACHIDONATE

???(??):: 5,8,11,14-Eicosatetraenoic acid, methyl ester, (all-Z)-;ARACHIDONIC ACID METHYL ESTER;(5Z,8Z,11Z,14Z)-Methyl icosa-5,8,11,14-tetraenoate;methyl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate;Einecs 219-900-1;METHYL ARACHIDONATE;Arachidonic acid methyl;Arachidonic Methyl Ester;Ethyl Acetate Impurity 111;Methyl arachidonate[A9298]

CBNumber:: CB0773227

???:: C21H34O2

??? ??:: 318.49

MOL ??:: 2566-89-4.mol

MSDS ??:: SDS

?? ?? 138

METHYL ARACHIDONATE ??

?? ?: 200-205℃ (1-2 Torr)

??: 0.9168 g/cm3

???: 1.4875 (589.3 nm 20℃)

?? ??: 2-8°C

???: ?????: 50mg/mL, ??, ??

??? ??: ??

??: ??

???? ??: Mortierella alpina

BRN: 1714445

???: ???

InChI: 1S/C21H34O2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21(22)23-2/h7-8,10-11,13-14,16-17H,3-6,9,12,15,18-20H2,1-2H3/b8-7-,11-10-,14-13-,17-16-

InChIKey: OFIDNKMQBYGNIW-ZKWNWVNESA-N

SMILES: CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OC

LogP: 7.466 (est)

?? ? ?? ??
?? ? ???? ?? (GHS)

??? ??	F,Xn,N
?? ???? ??	19-67-65-50/53-38-11
?????	9-16-29-33-60-61-62
????(UN No.)	UN 3183 4.2/PG 3
WGK ??	3
F ??????	10-21-23
?? ??	4.2
????	I
???? ???	10 - Combustible liquids

????(GHS):

?? ?:

Danger

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	P- ??
H304	??? ??? ???? ???? ? ??	?? ?????	?? 1	??
H315	??? ??? ???	????? ?? ?????	?? 2	??	P264, P280, P302+P352, P321,P332+P313, P362
H336	?? ?? ???? ??? ? ??	?????? ?? ??(1? ??);????	?? 3	??	P261, P271, P304+P340, P312,P403+P233, P405, P501
H410	??? ??? ?? ????? ?? ???	?? ????? ?? - ??	?? 1	??	P273, P391, P501

??????:

P261	??·?·??·???·??·...·????? ??? ????.
P273	???? ???? ???.
P301+P310	???? ?? ????(??)? ??? ????.
P331	??? ?? ???.
P501	...? ??? / ??? ?? ???.

NFPA 704

	3
2		0

METHYL ARACHIDONATE C??? ??, ??, ??

??

Arachidonic acid is the keystone essential fatty acid at the origin of the arachidonic acid cascade. It is converted by cyclooxygenase, lipoxygenase, and epoxygenase enzymes into more than one hundred fifty different potent primary autacoid metabolites in species ranging from fungi to plants to mammals. Arachidonic acid is stored in tissue phospholipids in esterified form, where it comprises a small but critically controlled percentage of the polyunsaturated fatty acid pool. Arachidonic acid content is frequently measured by the saponification of the lipid fraction followed by methyl esterification and gas chromatographic analysis of the resulting FAME (fatty acid methyl ester) compounds. Arachidonic acid methyl ester can also be incorporated into dietary regimens or fed to cultured cells as a source of exogenous arachidonate.

??

ChEBI: A fatty acid methyl ester resulting from the formal condensation of the carboxy group of arachidonic acid with methanol.

Biochem/physiol Actions

Unlike most unsaturated fatty acid methyl esters, methyl arachidonate is a potent activator of protein kinase C at 550μM. At the low end of the effective concentration range, the effect is due to cyclooxygenase products, while lipoxygenase products mediate the effect at higher concentrations.

METHYL ARACHIDONATE ?? ?? ? ???

???

MQCWCUDQEBWUAM-AWVFLLPBSA-N 2H-Pyran, 2-[(6-chloro-2-hexyn-1-yl)oxy]tetrahydro- 2-Hexyne, 1-bromo-6-chloro- 2-Hexyn-1-ol, 6-chloro- magnesium,hept-1-yne,bromide. Fandachem 5-Octenoic acid, 8-oxo-, methyl ester, (5Z)- 1,4-???? METHYL CIS CIS-11 14-EICOSADIENOATE

?? ??

????? CIS-7,10,13,16,19-DOCOSAPENTAENOIC ACID METHYL ESTER

METHYL ARACHIDONATE ?? ??

???( 138)?? ??

???	??	???	??	?? ?	??
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Aladdin Scientific		tp@aladdinsci.com	United States	57505	58

METHYL ARACHIDONATE ?? ??:

????? ARACHIDONIC ACID ETHYL ESTER 1,2-DI5,8,11,14(ALL-CIS)EICOSATETRAENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE METHYL ARACHIDONATE 1,3-DIARACHIDONIN 1-OCTADECANOYL-2-[(CIS,CIS,CIS,CIS)-5,8,11,14-EICOSATETRAENOYL]-SN-GLYCERO-3-PHOSPHOCHOLINE Omega3-Methyl?Arachidonate?(8c,?11c,14c,?17c?) 1-O-HEXADECYL-2-ARACHIDONYL-SN-GLYCERO-3-PHOSPHOCHOLINE ALL CIS MONOARACHIDONIN 1-STEAROYL-2-ARACHIDONOYL-SN-GLYCEROL ARACHIDONIC ACID PROPYL ESTER DL-ARACHIDOYL CARNITINE CHLORIDE TRIARACHIDONIN CHOLESTERYL ARACHIDONATE OMEGA-3-METHYL ARACHIDONATE CHOLESTERYL ARACHIDONATE, [ARACHIDONATE-1-14C] 1-HEXADECANOYL-2-[(CIS,CIS,CIS,CIS)-5,8,11,14-EICOSATETRAENOYL]-SN-GLYCERO-3-PHOSPHOCHOLINE PHOSPHATIDYLINOSITOL, L-ALPHA-1-STEAROYL-2- ARACHIDONYL, [ARACHIDONYL-1-14C]-

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