ChemicalBook >?? ???? >11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate 17-valerate

11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate 17-valerate

11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate 17-valerate ??? ???

?? ??:: 72064-79-0

???:: 11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate 17-valerate

???(??):: Prednisolone valerate acetate;Lidomex;Spirazon;Acepreval;Prednival 21-acetate;Prednisone Impurity 3;Nitisinone Impurity 4;Prednisolone Valeroacetate;Methylprednisolone Impurity 29;Prednisolone 17-valerate 21-acetat

CBNumber:: CB0897699

???:: C28H38O7

??? ??:: 486.61

MOL ??:: 72064-79-0.mol

?? ?? 65

11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate 17-valerate ??

?? ?: 502.49°C (rough estimate)

??: 1.1134 (rough estimate)

???: 1.5800 (estimate)

???: ?????(?? ???), ???(?? ???)

??? ??: ??

?? ?? (pKa): 14.05±0.70(Predicted)

??: ???

?? ? ?? ??
?? ? ???? ?? (GHS)

??	LD50 ipr-mus: 1360 mg/kg OYYAA2 20,195,80

????(GHS):

?? ?:

Warning

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	P- ??
H341	???? ??? ??? ??? ??? (????? ???? ????? ???? ???? ???? ??? ?? ????? ??? ???? ??)	???? ???? ??	?? 2	??	P201,P202, P281, P308+P313, P405,P501
H361	?? ?? ????? ??? ??? ??? ???	???? ??	?? 2	??	P201, P202, P281, P308+P313, P405,P501
H373	??? ?? ?? ???? ??(??, ??? ?? ??? ?? ??? ??)? ??? ??? ? ??	?? ???? ?? - ?? ??	?? 2	??	P260, P314, P501

??????:

P201	?? ? ?? ???? ?????.
P202	?? ?? ?? ??? ?? ???? ??? ???? ???.
P260	??·?·??·???·??·...·????? ???? ???.
P281	???? ?? ???? ?????
P308+P313	?? ?? ??? ???? ???? ??· ??? ????.
P314	???? ??? ???? ??·??? ????.
P405	???? ?????.
P501	...? ??? / ??? ?? ???.

11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate 17-valerate C??? ??, ??, ??

??

Prednisolone 21-Acetate 17-Valerate is a derivative of Prednisolone (P703740), which is a synthetic corticosteroid, metabolically interconvertible with prednisone, and an impurity of Hydrocortisone (H714615). Prednisolone 21-Acetate 17-Valerate is used in multifunctional nanoemulsion platform for imaging guided therapy evaluated in experimental cancer.

Safety Profile

Poison by subcutaneous route.Moderately toxic by other routes. An experimentalteratogen. Other experimental reproductive effects.

11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate 17-valerate ?? ?? ? ???

???

?? ??

11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate 17-valerate ?? ??

???( 65)?? ??

???	??	???	??	?? ?	??
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11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate 17-valerate ?? ??:

??????-21-???? ?????? Prednisolone 21-trimethylacetate Deprodone FEMA 3332 1,4-PREGNADIEN-11-BETA, 17,21-TRIOL-3,20-DIONE 17-VALERATE-21-ACETATE 11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate 17-valerate 1,3-DIACETOXYACETONE

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