4-??????
4-?????? ??
???
248-250 °C(lit.)
?? ?
260.71°C (rough estimate)
??
1.2377 (rough estimate)
???
1.5426 (estimate)
?? ??
Sealed in dry,Room Temperature
???
DMSO (?? ???), ??????? (?? ???), ??? (?? ???)
???
DMSO(?? ???), ???????(?? ???), ???(?? ???)
??? ??
?? ??? ??
?? ?? (pKa)
4.41(at 25℃)
??
???
BRN
1365308
InChI
InChI=1S/C9H7ClO2/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-6H,(H,11,12)
InChIKey
GXLIFJYFGMHYDY-ZZXKWVIFSA-N
SMILES
C(O)(=O)C=CC1=CC=C(Cl)C=C1
CAS ??????
1615-02-7(CAS DataBase Reference)
NIST
p-Chlorocinnamic acid(1615-02-7)
EPA
2-Propenoic acid, 3-(4-chlorophenyl)- (1615-02-7)
??
?? ? ?? ??
?? ? ???? ?? (GHS)
??? ??
Xn,Xi
?? ???? ??
22-36/37/38-20/21/22
?????
36-28A-26-24/25
WGK ??
3
RTECS ??
GD8490000
?? ?? ??
Irritant
HS ??
29163990
???? ???
11 - Combustible Solids
Hazard Classifications
Acute Tox. 4 Oral
????(GHS):
?? ?:
Warning
??·?? ??:
??
??·?? ??
?? ??
??
?? ?
?? ??
P- ??
H302 ??? ???
?? ?? ?? - ??
?? 4
??
P264, P270, P301+P312, P330, P501
H315 ??? ??? ???
????? ?? ?????
?? 2
??
P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ???
?? ? ?? ?? ??? ??
?? 2A
??
P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ??
?? ???? ?? - 1? ??;???? ??
?? 3
??
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P270 ? ??? ??? ??? ???, ???? ???? ???.
P280 ????/???/???/?????? ?????.
P304+P340 ???? ??? ??? ?? ??? ??? ???? ?? ??? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P405 ???? ?????.
P501 ...? ??? / ??? ?? ???.
NFPA 704
4-?????? C??? ??, ??, ??
??? ??
white to light yellow crystal powder
??
4-Chlorocinnamic Acid is a derivative of Cinnamic Acid (C442030) and plays an important role in the development of plants. 4-Chlorocinnamic Acid may also show potential antimicrobial, antioxidant, anti-inflammatory, and antitumoral activity.
Purification Methods
Recrystallise the acid from EtOH or aqueous EtOH (charcoal). UV has max at 275nm (EtOH). [Walling & Wolfstirn J Am Chem Soc 69 852 1947, Beilstein 9 H 596, 9 II 395, 9 III 2727, 9 IV 2033.]
4-?????? ?? ?? ? ???
???
?? ??
4-?????? ?? ??
???( 406)?? ??
Americas 1
Belgium 3
Canada 1
China 281
Czech Republic 1
Europe 3
Germany 10
India 29
Japan 4
Slovakia 1
Spain 1
Switzerland 3
United Kingdom 22
United States 46
Global 406
