3-Amino-5-bromobenzotrifluoride
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3-Amino-5-bromobenzotrifluoride ??
- ?? ?
- 220-223 °C (lit.)
- ??
- 1.697 g/mL at 25 °C (lit.)
- ???
- n
20/D 1.528(lit.)
- ???
- >230 °F
- ?? ??
- Keep in dark place,Inert atmosphere,Room temperature
- ???
- ?????(?? ???), ???(?? ???)
- ?? ?? (pKa)
- 2.30±0.10(Predicted)
- ??? ??
- ??
- ??
- ??~??
- InChI
- InChI=1S/C7H5BrF3N/c8-5-1-4(7(9,10)11)2-6(12)3-5/h1-3H,12H2
- InChIKey
- HJTLKVYOWNTDPF-UHFFFAOYSA-N
- SMILES
- C1(N)=CC(C(F)(F)F)=CC(Br)=C1
- CAS ??????
- 54962-75-3(CAS DataBase Reference)
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- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | Xi | ||
|---|---|---|---|
| ?? ???? ?? | 36/37/38 | ||
| ????? | 26-36 | ||
| WGK ?? | 3 | ||
| ?? ?? ?? | Irritant | ||
| ?? ?? | 6.1 | ||
| HS ?? | 29214300 | ||
| ???? ??? | 11 - Combustible Solids | ||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
3-Amino-5-bromobenzotrifluoride C??? ??, ??, ??
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3-Amino-5-bromobenzotrifluoride is an organic synthetic reagent or pharmaceutical intermediate component used in the synthesis of other organic compounds such as 3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline, fluorinated 2-benzylphthalazine-1 (2H)-one, 1-phthalazinamine and 1-alkoxy/benzyloxyphthalazine derivatives. It can also be used to prepare the targeted anti-cancer drug Nilotinib, which can be used to treat chronic granulocytic leukaemia (CML).??? ??
White solid??
3-Amino-5-bromobenzotrifluoride may be used in the synthesis of 3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline.???
3-Amino-5-bromobenzotrifluoride has acute toxicity (oral, inhalation,dermal), it causes skin irritation and eye irritation.3-Amino-5-bromobenzotrifluoride ?? ?? ? ???
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3-Amino-5-bromobenzotrifluoride ?? ??
???( 384)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| Jinan Qinmu Fine Chemical Co.,Ltd. | 18660799346 |
sales@qinmuchem.com | China | 1006 | 58 |
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| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 |
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sales@acrospharmatech.com | United States | 988 | 55 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29766 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 |
sales@ansciepchem.com | CHINA | 4241 | 58 |
3-Amino-5-bromobenzotrifluoride ?? ??:
??????? ??? ?????????? ???(???????)????? 1,4-??(????????)?? 6-??? ???? 3-?????? 3-????? 2,3-???????? ???????????????
3-Fluorobenzotrifluoride
2-Methylbenzotrifluoride
Nilotinib N-Oxide
4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid
4-(pyridine-2-yl) pyrimidin-2-amine
3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline
3-Iodo-4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]benzamide
4-Amino-3-bromobenzotrifluoride