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D-(+)-??OSE

D-(+)-??OSE
D-(+)-??OSE ??? ???
?? ??:
3458-28-4
???:
D-(+)-??OSE
???(??):
D-(+)-??OSE;D-(+)-???;D-(+)-???(D-(+)-MANNOSE);????
???:
D-Mannose
???(??):
D-MANNOPYRANOSE;D-(+)-MANNOSE;Aldohexos;D-MANOSE;α-D-mannose;D-MAN;CARUBINOSE;D-MannMtol;d-[1,2,3-13C3]Mannose;DL-allo-2,3,4,5,6-Pentahydroxy-hexanal
CBNumber:
CB1175305
???:
C6H12O6
??? ??:
180.16
MOL ??:
3458-28-4.mol
MSDS ??:
SDS

D-(+)-??OSE ??

???
133-140 °C(lit.)
??
14 º (589nm, c=10, H2O)
?? ?
232.96°C (rough estimate)
??
1,539 g/cm3
???
1.5730 (estimate)
?? ??
room temp
???
H2O: 50 mg/mL
??? ??
??
?? ?? (pKa)
12.08(at 25℃)
??
???
???? ??
wood
?? ??
[α]20/D +13.8±0.5°, 24 hr, c = 10% in H2O
???
2480g/L(17℃)
??
Hygroscopic
?? ??(λmax)
λ: 260 nm Amax: 0.1
λ: 280 nm Amax: 0.1
Merck
14,5747
BRN
1564373
Henry's Law Constant
1.2×109 mol/(m3Pa) at 25℃, Qin et al. (2021)
???
????. ?? ??. ?? ???? ???? ????.
?? ??
????
??? ?? ??
???
InChI
1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6/m1/s1
InChIKey
WQZGKKKJIJFFOK-ATJJXCEKSA-N
SMILES
OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O
LogP
-2.71 at 25℃
CAS ??????
3458-28-4(CAS DataBase Reference)
NIST
D-Mannose(3458-28-4)
EPA
D-Mannose (3458-28-4)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi
?? ???? ?? 36/37/38
????? 24/25-36-26
WGK ?? 3
F ?????? 3
TSCA TSCA listed
HS ?? 29400010
???? ??? 11 - Combustible Solids
???? ?? KE-23062
????(GHS): Exclamation Mark (GHS07)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
??????:
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P280 ????/???/???/?????? ?????.
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P332+P313 ?? ??? ??? ???? ??· ??? ????.
P337+P313 ?? ?? ??? ???? ???? ??· ??? ????.
NFPA 704
1 0

D-(+)-??OSE MSDS


D-(+)-Mannose

D-(+)-??OSE C??? ??, ??, ??

??? ??

White crystalline powder

??

D-Mannose is a carbohydrate that is important in the glycosylation of molecules in a variety of cellular processes. It is involved in N and O glycosylation of bovine why protein products, used in inf ant formulas. It is also responsible for the O-glycosylation of the T helper cell-derived cytokine interlukin-17A, an important cell-signaling molecule.

??

ChEBI: D-Mannopyranose having alpha-configuration at the anomeric centre.

?? ??

D-mannose is a simple sugar structurally related to glucose. It is absorbed slowly from the gastrointestinal tract, and then a large proportion of it is excreted into the urine.
D-(+)-Mannose has been used:
as a reference standard in monosaccharide analysis and quantification from sea squirts Ascidiella aspersa
as a medium component for the selection of P898012 sorgum seeds transfected with Agrobacterium
in segmented filamentous bacterium (SFB) medium supplement for culturing human cell lines
Mannose is an aldohexose carbohydrate. It is isomer of glucose with varying C2 position configuration. Majority of mannose is synthesised from its epimer glucose. It is part of the glycans present in endoplasmic reticulum (ER)/Golgi.

?? ??

Mannose is a monosaccharide.

???

D-mannose appears to be generally well tolerated in people. You should be cautious about using D-mannose if you are pregnant or breastfeeding, because there has not been enough study on its safety in these circumstances. Side effects of D-mannose may include: bloating and loose stools. D-mannose supplements should be used with caution if you have diabetes. It may make it harder to control your blood sugar. High doses of D-mannose may cause kidney damage.

Purification Methods

Crystallise -D(+)-mannose repeatedly from EtOH, aqueous 80% EtOH, AcOH or MeOH/propan-2-ol and then dry it in vacuo over P2O5 at 60o. [For 1H NMR and equilibr

D-(+)-??OSE ?? ?? ? ???

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D-(+)-??OSE ?? ??

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D-(+)-??OSE ?? ??:

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