(R)-(+)-Dropropizine
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(R)-(+)-Dropropizine ??
- ???
- 98-100°
- ??
- D25 -10° (c = 1.0 in ethanol)
- ?? ?
- 412.7±34.0 °C(Predicted)
- ??
- 1.168±0.06 g/cm3(Predicted)
- ?? ??
- 2-8°C
- ???
- ??????(??), ???(??)? ???
- ?? ?? (pKa)
- 14.21±0.20(Predicted)
- ??
- ???? ?????
- ?? ??
- ???(???)
- InChI
- 1S/C13H20N2O2/c16-11-13(17)10-14-6-8-15(9-7-14)12-4-2-1-3-5-12/h1-5,13,16-17H,6-11H2/t13-/m1/s1
- InChIKey
- PTVWPYVOOKLBCG-CYBMUJFWSA-N
- SMILES
- N1(CCN(CC1)c2ccccc2)C[C@@H](O)CO
- CAS ??????
- 99291-24-4(CAS DataBase Reference)
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| WGK ?? | WGK 3 | ||
|---|---|---|---|
| ???? ??? | 11 - Combustible Solids | ||
| Hazard Classifications | Acute Tox. 4 Oral | ||
| ?? | LD50 in mice, rats (mg/kg): 1287.2, 886.6 orally; 408.0, 401.3 i.p. (Borsa) |
| ????(GHS): |
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| ?? ?: | Warning | ||||||||||||||
| ??·?? ??: |
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| ??????: |
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(R)-(+)-Dropropizine C??? ??, ??, ??
??
Levodropropizine is an antitussive with antiinflammatory activity, the L-isomer of dropropizine. Compared with the racemate, levodropropizine is reported to have less sedative potential and better therapeutic index, while maintaining the the same efficacy levels as an antitussive and antiinflammatory.??
R-Form of Dropropizine (D681495). (R)-(+)-Dropropizine is a cough suppressive phenylpiperazine derivative. (R)-(+)-Dropropizine is an antitussive and central sedative therapeutic agent.(R)-(+)-Dropropizine ?? ?? ? ???
???
?? ??
(R)-(+)-Dropropizine ?? ??
???( 116)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
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(R)-(+)-Dropropizine ?? ??:
???? ??? ???? ??? ???? ?? P 1200 ?????? ??????? ??????? ???????? ???? ???(1-)-2-???? ????? 1-????????? ???????? ?????? R-(-)-???? ???? ???? ??? 2-??-1,3-?????
PHENYL VALERATE
Dropropizine
2-Ethylhexyl ferulate
Levonorgestrel
Levosimendan
Potassium (R)-[(3-ethoxy-1-methyl-3-oxoprop-1-enyl)amino]phenylacetate