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5-(5-chloro-1-(2-fluorophenyl)-2-oxopentyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate

5-(5-chloro-1-(2-fluorophenyl)-2-oxopentyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate ??? ???
?? ??:
1056459-37-0
???:
5-(5-chloro-1-(2-fluorophenyl)-2-oxopentyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate
???(??):
CHLOROBUTYRYL ALOG;Prasugrel Impurity K;Prasugrel Impurity E;Prasugrel chloride impurity;Prasugrel Impurity OXTPback;Prasugrel chlorobutyl analog;Prasugrel Ring Opened Degraden;5-(5-chloro-1-(2-fluorophenyl);Prasugrel 5-Chloro-2-pentanone;Prasugrel Hydrochloride EP Impurity E
CBNumber:
CB12655384
???:
C20H21ClFNO3S
??? ??:
409.9020432
MOL ??:
1056459-37-0.mol

5-(5-chloro-1-(2-fluorophenyl)-2-oxopentyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate ??

?? ?
522.6±50.0 °C(Predicted)
??
1.312±0.06 g/cm3(Predicted)
?? ?? (pKa)
3.90±0.20(Predicted)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
????(GHS): Exclamation Mark (GHS07)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? P264, P270, P301+P312, P330, P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ??
??????:
P280 ????/???/???/?????? ?????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

5-(5-chloro-1-(2-fluorophenyl)-2-oxopentyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate C??? ??, ??, ??

??

Prasugrel 5-Chloro-2-pentanone is an impurity of Prasugrel Hydrochloride(P701150). A novel antiplatelet agent; it is a third-generation thienopyridine. Antiplatelet agent Prasugrel showed greater platelet inhibition and decreased incidence of ischemic events than Clopidogrel but may induce increased incidence of bleeding in patient with acute coronary syndrome

5-(5-chloro-1-(2-fluorophenyl)-2-oxopentyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate ?? ?? ? ???

???

?? ??


5-(5-chloro-1-(2-fluorophenyl)-2-oxopentyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate ?? ??

???( 46)?? ??
??? ?? ??? ?? ?? ? ??
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5-(5-chloro-1-(2-fluorophenyl)-2-oxopentyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate ?? ??:

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