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1,1,3-????????

1,1,3-????????
1,1,3-???????? ??? ???
?? ??:
921-03-9
???:
1,1,3-????????
???(??):
1,1,3-????????
???:
1,1,3-Trichloroacetone
???(??):
1,1,3-trichloro-2-propanon;1,1,3-TCA;1,1,3-TrichL;1,1,3-TRICHLOROACETONE;1,1,3-TRICHLOROPROPANONE;1,1,3-TRICHLORO-2-PROPANONE;2-Propanone, 1,1,3-trichloro-;1,1,3-Trichloroacetone, ≥ 80.0%;1,1,3-TRICHLOROACETONE, WACKER QUALITY;Fluphenazine Dihydrochloride Impurity 8
CBNumber:
CB1275319
???:
C3H3Cl3O
??? ??:
161.41
MOL ??:
921-03-9.mol

1,1,3-???????? ??

???
9-11 °C(lit.)
?? ?
88-90 °C76 mm Hg(lit.)
??
1.512 g/mL at 20 °C(lit.)
???
30-350Pa at 20-50℃
???
n20/D 1.491
???
80
?? ??
Refrigerator, under inert atmosphere
???
?????, ???? ???
??? ??
??
??
?? ??
BRN
1746647
InChIKey
ZWILTCXCTVMANU-UHFFFAOYSA-N
LogP
0.45
CAS ??????
921-03-9(CAS DataBase Reference)
NIST
2-Propanone, 1,1,3-trichloro-(921-03-9)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? T+,N
?? ???? ?? 25-26-34-50/53-68-21
????? 26-36/37/39-45-60-61-28
????(UN No.) UN 3390 6.1/PG 1
WGK ?? 3
RTECS ?? UC3840000
?? ?? 6.1(b)
???? III
HS ?? 29147000
?? mmo-sat 50 mL/plate ENMUDM 7,163,85
????(GHS): Corrosion (GHS05)Skull and Crossbones (GHS06)Environment (GHS09)
?? ?: Danger
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H314 ??? ?? ??? ?? ??? ??? ????? ?? ????? ?? 1A, B, C ?? P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H330 ???? ???? ?? ?? ?? ?? ?? 1, 2 ?? P260, P271, P284, P304+P340, P310,P320, P403+P233, P405, P501
H410 ??? ??? ?? ????? ?? ??? ?? ????? ?? - ?? ?? 1 ?? P273, P391, P501
??????:
P273 ???? ???? ???.
P280 ????/???/???/?????? ?????.
P303+P361+P353 ??(?? ????)? ??? ??? ?? ??? ??? ????? ??? ?? ????/?????.

1,1,3-???????? C??? ??, ??, ??

??

1,1,3-Trichloroacetone is direct-acting mutagens in the Ames/Salmonella assay. It is precursor for the generation of 1,3-dihalo oxyallyl intermediates, which undergo [4 + 3] cycloadditions with a host of 1,3-diene systems.

??? ??

Light yellow transparent liquid

??

1,1,3-Trichloroacetone was used in base-induced solvolyses of [3.2.1]Bicyclic α,α′-dichloro ketones.

Safety Profile

Poison by inhalation. Corrosiveand lachrymator. Mutation data reported. Combustibleliquid. When heated to decomposition it emits toxic fumesof Clí.

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