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FSB

FSB ??? ???
?? ??:
760988-03-2
???:
FSB
???(??):
FSB staining solution;Benzoic acid, 3,3'-[(2-fluoro-1,4-phenylene)di-(1E)-2,1-ethenediyl]bis[6-hydroxy-;5-[(E)-2-[4-[(E)-2-(3-carboxy-4-hydroxyphenyl)ethenyl]-3-fluorophenyl]ethenyl]-2-hydroxybenzoic acid
CBNumber:
CB14665963
???:
C24H17FO6
??? ??:
420.39
MOL ??:
760988-03-2.mol
MSDS ??:
SDS

FSB ??

???
294 °C (decomp)
?? ?
663.3±55.0 °C(Predicted)
??
1.490±0.06 g/cm3(Predicted)
???
87°C
?? ??
2-8°C
???
DMSO: 200 mg/ml
??? ??
??
?? ?? (pKa)
3.08±0.10(Predicted)
??
yellow
?? ??(λmax)
λ: 360-380 nm Amax: 0.6-0.9
InChIKey
DZXZHGCGNRRJEG-WMWQKROPSA-N
SMILES
Fc1c(ccc(c1)\C=C\c3cc(c(cc3)O)C(=O)O)\C=C\c2cc(c(cc2)O)C(=O)O
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
WGK ?? 2
???? ??? 11 - Combustible Solids
????(GHS): Exclamation Mark (GHS07)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ??
H413 ??? ??? ?? ????? ??? ??? ?? ?? ????? ?? - ?? ?? 4
??????:
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P280 ????/???/???/?????? ?????.
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P321 (…) ??? ???.
P332+P313 ?? ??? ??? ???? ??· ??? ????.
P362 ??? ??? ?? ?? ?? ?????
NFPA 704
0
2 0

FSB C??? ??, ??, ??

??

FSB is a fluorescent probe that has been used for the detection of amyloid plaques in human postmortem brain from patients with Alzheimer’s disease and of curli amyloid fibers in E. coli biofilms. It has also been used to label tau inclusions in mouse and human brain sections and in mouse spinal cord following intravenous injection. FSB has excitation/emission maxima of 390/520 nm, respectively.

??

FSB is useful for staining plaques and neurofibrillary tangles.

FSB ?? ?? ? ???

???

?? ??


FSB ?? ??

???( 16)?? ??
??? ?? ??? ?? ?? ? ??
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