heparinase I
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heparinase I ??
- ?? ??
- -20°C
- ??? ??
- lyophilized solid
- ??
- White to off-white
- Specific Activity
- ≥200units/mg protein (enzyme + BSA)
- ?? ??
- ?? ?? ??
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| WGK ?? | 3 | ||
|---|---|---|---|
| ???? ??? | 11 - Combustible Solids | ||
| Hazard Classifications | Resp. Sens. 1 |
| ????(GHS): |
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|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ?? ?: | Danger | ||||||||||||||
| ??·?? ??: |
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| ??????: |
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heparinase I C??? ??, ??, ??
??
Heparinase I from Flavobacterium heparinum has been used:- in the digestion of plasma samples
- to study the effect of medium, washing and sonication on the infectivity of Chlamydia pneumonia
- in enzymatic removal of heparan sulfate from the surface of human rhabdomyosarcoma cells
Biochem/physiol Actions
Heparinase I from Flavobacterium heparinum acts by cleaving the α-glycoside linkage at AT III binding site in heparin. This results in small oligosaccharide fragments and heparinase I neutralizes the protein′s action of anticoagulation. Therefore it might replace the use of protamine in reversing heparin induced anticoagulation after coronary artery bypass surgery. Heparinase I possesses a half-life of 15-18 minutes.heparinase I ?? ?? ? ???
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?? ??
heparinase I ?? ??
???( 42)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| Creative Enzymes | 1-516-855-7709 |
info@creative-enzymes.com | United States | 8748 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 |
laboratory@coreychem.com | China | 30203 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +86-15965530500 |
nickzhang@hangyubiotech.com | China | 9937 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501 |
product@acmec-e.com | China | 33301 | 58 |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 |
cooperation@kean-chem.com | China | 40048 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 |
3bsc@sina.com | China | 15815 | 69 |
| Sinopharm Chemical Reagent Co,Ltd. | 86-21-63210123 |
sj_scrc@sinopharm.com | China | 9791 | 79 |
| Nanjing Dulai Biotechnology Co., Ltd. | 025-84699383-8003;025-846993838003-8003 18013301590 |
njduly@126.com | China | 3293 | 55 |
| Shanghai Macklin Biochemical Co.,Ltd. | 15221275939 15221275939 |
shenlinxing@macklin.cn | China | 15775 | 55 |
| Shanghai Baoman Biotechnology Co., Ltd. | 021-62130998 |
baomanbio@163.com | China | 192 | 55 |
heparinase I ?? ??:
???(II) ????????? ?????? ?? ????????? ??????? ?? ????? ??(2,2,6,6-?????-3,5-???????) ???? ????????? ??????? ?2?
SALCOMINE
Tosylmethyl isocyanide
DICHLORO(ETHYLENEDIAMINE)PLATINUM(II)
PHENYLSELENOL
TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III)
METHYL ISOCYANOACETATE
N-BUTYLISOCYANIDE
1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE
TERT-BUTYL ISOCYANIDE
Tris(2,4-pentanedionato)chroMiuM(III)
Benzyl isocyanide
Ethyl isocyanoacetate