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4-Hydroxyisophthalonitrile

4-Hydroxyisophthalonitrile ??? ???
?? ??:
34133-58-9
???:
4-Hydroxyisophthalonitrile
???(??):
Febuxostat-13;Febuxostat 30;2,4-Dicyanophenol;2,4-DIAMINO-PHENOL;FeBuxostat Impurity 35;4-Hydroxyisophthalonitrile;4-hydroxybenzene-1,3-dicarbonitrile;1,3-Benzenedicarbonitrile,4-hydroxy-;Febuxostat Impurity 20/4-hydroxyisophthalonitrile
CBNumber:
CB1801374
???:
C8H4N2O
??? ??:
144.13
MOL ??:
Mol file

4-Hydroxyisophthalonitrile ??

?? ?
319℃
??
1.34
???
150℃
?? ??
Keep in dark place,Inert atmosphere,Room temperature
???
DMSO(?? ???), ???(?? ???)
??? ??
??
??? ??
??? ??
?? ?? (pKa)
5.04±0.18(Predicted)
??
?????
??? ?? ??
4-Hydroxyisophthalonitrile (34133-58-9)

??

HS ?? 2926907090

4-Hydroxyisophthalonitrile C??? ??, ??, ??

??

4-Hydroxy-1,3-benzenedicarbonitrile is used in the preparation of febuxostat (F229000), a non-purine xanthine oxidase inhibitor used as a treatment for hyperuricaemia and chronic gout.

4-Hydroxyisophthalonitrile ?? ?? ? ???

???

?? ??


4-Hydroxyisophthalonitrile ?? ??

???( 107)?? ??
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