ChemicalBook >?? ???? >5-[4'-(Bromomethyl)-[1,1'-biphenyl]-2-yl]-2-(triphenylmethyl)-2H-tetrazole

5-[4'-(Bromomethyl)-[1,1'-biphenyl]-2-yl]-2-(triphenylmethyl)-2H-tetrazole

5-[4'-(Bromomethyl)-[1,1'-biphenyl]-2-yl]-2-(triphenylmethyl)-2H-tetrazole ??? ???

?? ??:: 133051-88-4

???:: 5-[4'-(Bromomethyl)-[1,1'-biphenyl]-2-yl]-2-(triphenylmethyl)-2H-tetrazole

???(??):: 5-[2-[4-(bromomethyl)phenyl]phenyl]-2-trityltetrazole;CBB Ester;Valsartan Impurity 25;Olmesartan Impurity 15;Olmesartan Ester Impurity 75;4-Bromomethyl-[2'-(2-Trityl-2H;Olmesartan Medoxomil Impurity 75;Candesartan Bromo N2-Trityl Impurity;5-[4'-(BroMoMethyl)-[1,1'-biphenyl]-2-yl]-2-(triph;2-(N-Triphenyl methyl tetrazyl)-4’-bromo methyl biphenyl

CBNumber:: CB21016882

???:: C33H25BrN4

??? ??:: 557.48

MOL ??:: 133051-88-4.mol

?? ?? 97

5-[4'-(Bromomethyl)-[1,1'-biphenyl]-2-yl]-2-(triphenylmethyl)-2H-tetrazole ??

???: 135-137 °C(Solv: ethyl ether (60-29-7))

?? ?: 718.4±70.0 °C(Predicted)

??: 1.28±0.1 g/cm3(Predicted)

?? ??: -20°C Freezer, Under inert atmosphere

???: ????? (??), ??? (??, ??)? ??

??? ??: ??

??? ??: ??? ??

?? ?? (pKa): -0.09±0.12(Predicted)

??: ???? ?? ???

???: ??? ???

InChI: InChI=1S/C33H25BrN4/c34-24-25-20-22-26(23-21-25)30-18-10-11-19-31(30)32-35-37-38(36-32)33(27-12-4-1-5-13-27,28-14-6-2-7-15-28)29-16-8-3-9-17-29/h1-23H,24H2

InChIKey: WROIFZUSIQAQBZ-UHFFFAOYSA-N

SMILES: N1=C(C2=CC=CC=C2C2=CC=C(CBr)C=C2)N=NN1C(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1

?? ? ?? ??
?? ? ???? ?? (GHS)

HS ??	2933.99.8290

????(GHS):

?? ?:

Warning

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	?? ??	P- ??
H315	??? ??? ???	????? ?? ?????	?? 2	??		P264, P280, P302+P352, P321,P332+P313, P362
H319	?? ?? ??? ???	?? ? ?? ?? ??? ??	?? 2A	??		P264, P280, P305+P351+P338,P337+P313P

??????:

P264	?? ??? ?? ??? ????.
P264	?? ??? ?? ??? ????.
P280	????/???/???/?????? ?????.
P302+P352	??? ??? ??? ?? ????.
P305+P351+P338	?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P321	(…) ??? ???.
P332+P313	?? ??? ??? ???? ??· ??? ????.
P362	??? ??? ?? ?? ?? ?????

NFPA 704

	0
2		0

5-[4'-(Bromomethyl)-[1,1'-biphenyl]-2-yl]-2-(triphenylmethyl)-2H-tetrazole C??? ??, ??, ??

??? ??

White to Off-White Solid

??

An intermediate in the synthesis of Losartan and Valsartan.

5-[4'-(Bromomethyl)-[1,1'-biphenyl]-2-yl]-2-(triphenylmethyl)-2H-tetrazole ?? ?? ? ???

???

4-??-[2'-(2-???-2H-Tetr 4'-Methyl-2-cyanobiphenyl 5-[2-(4'-?????)]???? 2-???????????????? 2-(2-?????)-4,4-???-2-???? N-(2-HYDROXY-1,1-DIMETHYLETHYL)-2-METHOXYBENZENECARBOXAMIDE 4,4-DIMETHYL-2-(4'-METHYL-2-BIPHENYLYL)-2-OXAZOLINE ???????? 4-?????? ????????? ????? o-Anisic acid 2-Bromobenzonitrile

?? ??

???????????? N-????????????

5-[4'-(Bromomethyl)-[1,1'-biphenyl]-2-yl]-2-(triphenylmethyl)-2H-tetrazole ?? ??

???( 97)?? ??

???	??	???	??	?? ?	??
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5-[4'-(Bromomethyl)-[1,1'-biphenyl]-2-yl]-2-(triphenylmethyl)-2H-tetrazole ?? ??:

Dehydro Olmesartan OlMesartan Lactone IMpurity OlMesartan MedoxoMil Ethyl Methyl Analog 4,5-Bismethylene-1,3-dioxolan-2-one Olmesartan 4-(1-Methoxy-1-methylethyl)-2-propyl-1H-Imidazole-5-carboxylic acid ethyl ester 2-Propyl-1H-imidazole-4,5-dicarboxy acid Olmesartan Impurity 10 Olmesartan 4-(2-hydroxypropan-2-yl)-2-propyl-1H-imidazole-5-carboxylic acid 4,5-Dimethyl-1,3-dioxol-2-one Olmesartan Impurity 12 OlMesartan MedoxoMil Butyl IMpurity Diethyl 2-propylImidazoledicarbonate Olmesartan Impurity 16 Olmesartan medoxomil impurity I Olmesartan Medoxomil Methyl Ether 3,6-Dihydro-6,6-diMethyl-2-propyl-3-[[2'-[2-(triphenylMethyl)-2H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]Methyl]-4H-furo[3,4-d]iMidazol-4-one

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