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2114-02-5
???:
????????
???(??):
2-???-4-?????;????????;????????(AMIDINOTHIOUREA);2-???-4-??????
???:
Amidinothiourea
???(??):
ASU;GUANYLTHIOUREA;GTU;gutimine;1-amidino-2-thiourea;2-IMINO-4-THIOBIURET;Guthimin;guthimine;AMIDINOTHIOUREA;Guanphenisin BP
CBNumber:
CB2243166
???:
C2H6N4S
??? ??:
118.16
MOL ??:
2114-02-5.mol
MSDS ??:
SDS

???????? ??

???
171-173 °C(lit.)
?? ?
231.2±23.0 °C(Predicted)
??
1.301 (estimate)
???
1.5605 (estimate)
?? ??
Sealed in dry,Room Temperature
?? ?? (pKa)
11.89±0.70(Predicted)
??? ??
??? ?? ?? ??
??
???? ?????
??????(pH)
8.87 at 24.1℃ and 10g/L
???
7g/100mL(20℃)
BRN
1756620
InChI
InChI=1S/C2H6N4S/c3-1(4)6-2(5)7/h(H6,3,4,5,6,7)
InChIKey
OKGXJRGLYVRVNE-UHFFFAOYSA-N
SMILES
N(C(N)=N)C(N)=S
LogP
1.8 at 30℃ and pH7.86
CAS ??????
2114-02-5(CAS DataBase Reference)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi,Xn
?? ???? ?? 36/37/38-20/21/22
????? 26-37/39-24/25-23
????(UN No.) 2811
WGK ?? 3
RTECS ?? YR8250000
???? III
HS ?? 29309090
???? ??? 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
?? mouse,LD50,intraperitoneal,1440mg/kg (1440mg/kg),Pharmaceutical Chemistry Journal Vol. 30, Pg. 181, 1996.
???? ?? KE-05-0115
????(GHS): Exclamation Mark (GHS07)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ??
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P271 ?? ?? ??? ? ?? ???? ?????.
P280 ????/???/???/?????? ?????.
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
NFPA 704
1
2 0

???????? C??? ??, ??, ??

??? ??

white to off-white crystals or crystalline powder

??

2-Imino-4-thiobiuret is used in the design and synthesis of guanylthiourea derivatives which are potential inhibitors of plasmodium falciparum dihydrofolate reductase enzyme. 2-Imino-4-thiobiuret is also used as a reagent in recyclization reactions of N-arylmaleimides with polynucleophilic compounds.

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