ChemicalBook >?? ???? >3-???-4-????-N-[4-[[2-(??????)?????]????]??]???????

3-???-4-????-N-[4-[[2-(??????)?????]????]??]???????

3-???-4-????-N-[4-[[2-(??????)?????]????]??]??????? ??? ???

?? ??:: 852918-02-6

???:: 3-???-4-????-N-[4-[[2-(??????)?????]????]??]???????

???(??):: 3-???-4-????-N-[4-[[2-(??????)?????]????]??]???????

???:: 3-Chloro-4-fluoro-N-[4-[[2-(phenylcarbonyl)hydrazino]carbonyl]benzyl]benzenesulfonamide

???(??):: TCN 201;TCN 201-d5;N-[[4-(benzamidocarbamoyl)phenyl]methyl]-3-chloro-4-fluorobenzenesulfonamide;N-(4-(2-benzoylhydrazinecarbonyl)benzyl)-3-chloro-4-fluorobenzenesulfonaMide;4-[[[(3-Chloro-4-fluorophenyl)sulfonyl]aMino]Methyl]benzoic Acid 2-Benzoylhydrazide;3-Chloro-4-fluoro-N-[4-[[2-(phenylcarbonyl)hydrazino]carbonyl]benzyl]benzenesulfonamide;Benzoic acid, 4-[[[(3-chloro-4-fluorophenyl)sulfonyl]amino]methyl]-, 2-benzoylhydrazide;TCN 201,GluN1,Inhibitor,GluN2A,inhibit,iGluR,Ionotropic glutamate receptors,NMDAR,TCN201;3-Chloro-4-fluoro-N-[(4-{[2-(phenylcarbonyl)hydrazino]carbonyl}phenyl)methyl]benzenesulfonamide;TCN-201 N-(4-(2-benzoylhydrazinecarbonyl)benzyl)-3-chloro-4- fluorobenzenesulfonaMide

CBNumber:: CB22518750

???:: C21H17ClFN3O4S

??? ??:: 461.89

MOL ??:: 852918-02-6.mol

MSDS ??:: SDS

?? ?? 97

3-???-4-????-N-[4-[[2-(??????)?????]????]??]??????? ??

?? ??: 2-8°C

???: DMSO: ???5mg/mL(?? ??)

??? ??: ??

??: ???? ????

InChI: 1S/C21H17ClFN3O4S/c22-18-12-17(10-11-19(18)23)31(29,30)24-13-14-6-8-16(9-7-14)21(28)26-25-20(27)15-4-2-1-3-5-15/h1-12,24H,13H2,(H,25,27)(H,26,28)

InChIKey: FYIBXBFDXNPBSF-UHFFFAOYSA-N

SMILES: Fc1ccc(cc1Cl)S(=O)(=O)NCc2ccc(cc2)C(=O)NNC(=O)c3ccccc3

?? ? ?? ??
?? ? ???? ?? (GHS)

??? ??	Xi
?? ???? ??	22-36/37/38
?????	26-36/37/39
WGK ??	3
???? ???	11 - Combustible Solids
Hazard Classifications	Eye Irrit. 2 Skin Irrit. 2 STOT SE 3

????(GHS):

?? ?:

Warning

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	P- ??
H315	??? ??? ???	????? ?? ?????	?? 2	??	P264, P280, P302+P352, P321,P332+P313, P362
H319	?? ?? ??? ???	?? ? ?? ?? ??? ??	?? 2A	??	P264, P280, P305+P351+P338,P337+P313P
H335	?? ???? ??? ? ??	?? ???? ?? - 1? ??;???? ??	?? 3	??
H336	?? ?? ???? ??? ? ??	?????? ?? ??(1? ??);????	?? 3	??	P261, P271, P304+P340, P312,P403+P233, P405, P501

??????:

P261	??·?·??·???·??·...·????? ??? ????.
P264	?? ??? ?? ??? ????.
P264	?? ??? ?? ??? ????.
P271	?? ?? ??? ? ?? ???? ?????.
P280	????/???/???/?????? ?????.
P302+P352	??? ??? ??? ?? ????.
P305+P351+P338	?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

NFPA 704

	0
2		0

3-???-4-????-N-[4-[[2-(??????)?????]????]??]??????? C??? ??, ??, ??

??

TCN 201 is a novel NMDA receptor antagonist selective for NR2A- over NR2B-containing receptors.

Biochem/physiol Actions

TCN-201 is a sulphonamide derivative, that negatively modulates glycine binding to the GluN1 (glutamate receptor subunit) subunit of the receptor.

3-???-4-????-N-[4-[[2-(??????)?????]????]??]??????? ?? ?? ? ???

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3-???-4-????-N-[4-[[2-(??????)?????]????]??]??????? ?? ??

???( 97)?? ??

???	??	???	??	?? ?	??
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3-???-4-????-N-[4-[[2-(??????)?????]????]??]??????? ?? ??:

TCN 213

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