ADRENIC ACID
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ADRENIC ACID ??
- ?? ?
- 161-164.5 °C(Press: 0.07 Torr)
- ??
- 0.9220 g/cm3
- ?? ??
- −20°C
- ???
- ?????(???? ??), ???(?? ???)
- ?? ?? (pKa)
- 4.76±0.10(Predicted)
- ??? ??
- ??
- ??
- ??
- ???
- ???
- InChI
- 1S/C22H36O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-21H2,1H3,(H,23,24)/b7-6-,10-9-,13-12-,16-15-
- InChIKey
- TWSWSIQAPQLDBP-DOFZRALJSA-N
- SMILES
- C(O)(=O)CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| WGK ?? | 3 | ||
|---|---|---|---|
| ???? ??? | 10 - Combustible liquids |
ADRENIC ACID C??? ??, ??, ??
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Adrenic acid is a naturally occurring polyunsaturated fatty acid (PUFA) formed through a 2-??? ??
Docosa tetra enoic acid designates any straight chain 22:4 fatty acid.One isomer is of particular interest :
all-cis-7,10,13,16-docosa tetra enoic acid is an ω-6 fatty acid with the trivial name adrenic acid. This is a naturally occurring polyunsaturated fatty acid formed through a 2-carbon chain elongation of arachidonic acid. It is one of the most abundant fatty acids in the early human brain.
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Adrenic acid is considered a sort of storage form of arachidnoic acid because it can be retro-converted into arachidonic acid by enzymes. Arachidonic acid is relatively abundant especially in the phospholipids that are found in cellular membranes, and it is precursor for many hormone-like signaling molecules, e.g. prostaglandins and leukotrienes. It shall be liberated from the phospholipids by phospholipase enzymes before it can be converted into these signaling molecules. Omnivorous humans also consume small amounts of arachidonic acid with the diet, since arachidonic acid is found in small amounts in all animal products. Arachidonic acid is not found in higher plants. Arachidonic acid serves many important functions in the body, e.g. as a structural element in membrane phospholipids, and as precursor for signalling.?? ???
This long-chain, unsaturated fatty acid (FWfree-acid = 332.53 g/mol; CAS 28874-58-0), also known as adrenic acid and (7Z,10Z,13Z,16Z)- docosatetraenoic acid, inhibits arachidonyl-CoA synthetase, orarachidonate:CoA ligase and prostaglandin biosynthesis.ADRENIC ACID ?? ?? ? ???
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?? ??
ADRENIC ACID ?? ??
???( 83)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
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ADRENIC ACID ?? ??:
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Nervonic acid
CIS-6,9,12,15-OCTADECATETRAENOIC ACID*SO DIUM
cis-11-Eicosenoic acid
DELTA 7 CIS, 10 CIS,13 CIS, 16 CIS DOCOSATETRAENOIC ACID ETHYL ESTER
ADRENIC ACID
3(R,S)-HYDROXY-7(Z),10(Z),13(Z),16(Z)-DOCOSATETRAENOIC ACID
DELTA 7 CIS, 10 CIS,13 CIS, 16 CIS DOCOSATETRAENOIC ACID METHYL ESTER
3(R,S)-HYDROXY-7(Z),10(Z),13(Z),16(Z)-DOCOSATETRAENOIC ACID METHYL ESTER