ChemicalBook >?? ???? >(2-???-4,5-???-3-???)-[3-(????????)??]???

(2-???-4,5-???-3-???)-[3-(????????)??]???

(2-???-4,5-???-3-???)-[3-(????????)??]??? ??? ???

?? ??:: 132861-87-1

???:: (2-???-4,5-???-3-???)-[3-(????????)??]???

???(??):: (2-???-4,5-???-3-???)-[3-(????????)??]???

???:: (2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE

???(??):: PD 81,723;4,5-Dimethyl-3-[3-(trifluoromethyl)benzoyl]-2-thiophenamine;(2-Amino-4,5-dimethylthiophen-3-yl)(3-trifluoromethylphenyl) ketone;(3-Trifluoromethylphenyl)(2-amino-4-methyl-5-methyl-3-thienyl) ketone;(2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE;Methanone, (2-aMino-4,5-diMethyl-3-thienyl)[3-(trifluoroMethyl)phenyl]-;(2-amino-4,5-dimethyl-3-thiophenyl)-[3-(trifluoromethyl)phenyl]methanone;(2-Amino-4,5-dimethylthiophen-3-yl)-(3-(trifluoromethyl)phenyl)methanone

CBNumber:: CB2484082

???:: C14H12F3NOS

??? ??:: 299.31

MOL ??:: 132861-87-1.mol

?? ?? 43

(2-???-4,5-???-3-???)-[3-(????????)??]??? ??

???: 100-104 °C(Solv: ligroine (8032-32-4))

?? ?: 411.7±45.0 °C(Predicted)

??: 1.328±0.06 g/cm3(Predicted)

?? ??: Sealed in dry,2-8°C

???: DMSO: ~13mg/mL

??? ??: ??

??? ??: ??? ??

?? ?? (pKa): -1.36±0.13(Predicted)

??: ???

??

WGK ??	3

(2-???-4,5-???-3-???)-[3-(????????)??]??? C??? ??, ??, ??

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PD 81,723 is an allosteric potentiator that increases the functional effects of adenosine and adenosine analogs.

???? ??

Allosteric potentiator at the adenosine A 1 receptor; acts via agonist-dependent and -independent mechanisms. Enhances agonist affinity for, and increased t 1/2 of dissociation from, the receptor. Also inhibits basal and forskolin-stimulated adenylyl cyclase (AC) activity in A 1 receptors expressed in CHO cells, possibly via direct potentiation of constitutive receptor activity or by direct inhibition of AC. Active in vivo .

(2-???-4,5-???-3-???)-[3-(????????)??]??? ?? ?? ? ???

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(2-???-4,5-???-3-???)-[3-(????????)??]??? ?? ??

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???	??	???	??	?? ?	??
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(2-???-4,5-???-3-???)-[3-(????????)??]??? ?? ??:

3-(3-TRIFLUOROMETHYLBENZOYL)THIOPHENE 3-(3-METHYLBENZOYL)THIOPHENE (2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE 3-BENZOYLTHIOPHENE (2-Amino-3-thienyl)(phenyl)methanone 2-AMINO-3-BENZOYL-4,5-DIMETHYLTHIOPHENE

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