ChemicalBook >?? ???? >10-[2-?????????]?????
10-[2-?????????]?????
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![10-[2-?????????]?????](CAS/GIF/1094-08-2.gif)
10-[2-?????????]????? ??
- ???
- 223-225° (some decompn)
- ?? ??
- 2-8°C
- ???
- DMSO: ~60°C?? >5mg/mL, ??
- ??? ??
- ??
- ??
- ???
- Merck
- 13,3783
- ???
- ???
- InChI
- 1S/C19H24N2S.ClH/c1-4-20(5-2)15(3)14-21-16-10-6-8-12-18(16)22-19-13-9-7-11-17(19)21;/h6-13,15H,4-5,14H2,1-3H3;1H
- InChIKey
- VXPCQISYVPFYRK-UHFFFAOYSA-N
- SMILES
- Cl[H].CCN(CC)C(C)CN1c2ccccc2Sc3ccccc13
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- ?? ? ???? ?? (GHS)
| ??? ?? | Xn | ||
|---|---|---|---|
| ?? ???? ?? | 22 | ||
| WGK ?? | 3 | ||
| RTECS ?? | SO5002000 | ||
| ???? ??? | 11 - Combustible Solids | ||
| Hazard Classifications | Acute Tox. 4 Oral | ||
| ?? | LD50 s.c. in mice: 670 mg/kg (Farquharson, Johnston) |
10-[2-?????????]????? C??? ??, ??, ??
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Ethopropazine hydrochloride is a drug that shifts energy metabolism from mitochondrial respiration to glycolysis.??
ChEBI: The monohydrochloride salt of profenamine. An antimuscarinic, it is used for the symptomatic treatment of Parkinson's disease.?? ??
Ethopropazinehydrochloride, 10-[2-(diethylamino)propyl]phenothiazinemonohydrochloride (Parsidol), introduced to therapy in1954, has antimuscarinic activity and is especially useful inthe symptomatic treatment of parkinsonism. In this capacity,it has value in controlling rigidity, and it also has a favorableeffect on tremor, sialorrhea, and oculogyric crises.Clinical Use
Ethopropazine Hydrochloride is oftenused in conjunction with other antiparkinsonian drugs forcomplementary activity.Side effects are common with this drug but are usuallynot severe. Drowsiness and dizziness are the most commonside effects at ordinary dosage levels, and as the dose increases,xerostomia, mydriasis, and others become evident.It is contraindicated in conditions such as glaucoma becauseof its mydriatic effect.10-[2-?????????]????? ?? ?? ? ???
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10-[2-?????????]????? ?? ??
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10-[2-?????????]????? ?? ??:
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ETHOPROPAZINE
2-Aminoethylammonium chloride
diethazine
10-METHYLPHENOTHIAZINE
2-(Phenylthio)aniline
Ethopropazine Hydrochloride
1-(DIMETHYLAMINO)ISOPROPYLAMINE
N-Methyldiphenylamine
fenethazine
DIPHENYLAMINE HYDROCHLORIDE
N,N,N',N'-TETRAMETHYL-1,2-DIAMINOPROPANE
N-(2-amino-1-methylethyl)-N,N-diethylamine
N,N-DIETHYL-N',N'-DIMETHYLETHYLENE DIAMINE
N,N-DIETHYL-N'-PHENYLETHYLENEDIAMINE
N-MONODESMETHYL PROMETHAZINE