Sulprostone
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Sulprostone ??
- ???
- 79.25°C
- ??
- 1.1918 (rough estimate)
- ???
- 1.5650 (estimate)
- ?? ??
- -20°C
- ???
- DMSO: >5mg/mL
- ?? ?? (pKa)
- 4.63±0.40(Predicted)
- ??? ??
- ??
- ??? ??
- ??? ??
- ??
- ???? ?????
- InChIKey
- UQZVCDCIMBLVNR-TWYODKAFSA-N
- SMILES
- CS(=O)(=O)NC(=O)CCC\C=C/C[C@@H]1[C@@H](\C=C\[C@@H](O)COc2ccccc2)[C@H](O)CC1=O
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | T | ||
|---|---|---|---|
| ?? ???? ?? | 60-36/37/38 | ||
| ????? | 53-22-36/37-45 | ||
| WGK ?? | 3 | ||
| RTECS ?? | MJ8810000 | ||
| ???? ??? | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
||
| Hazard Classifications | Eye Irrit. 2 Repr. 1B Skin Irrit. 2 STOT SE 3 |
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| ?? | LD50 intraperitoneal in mouse: 18mg/kg |
Sulprostone MSDS
(Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(E,3R)-3-hydroxy-4-(phenoxy)but-1-enyl]-5-oxocyclopentyl]-N-methylsulfonylhept-5-enamide
Sulprostone C??? ??, ??, ??
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Sulprostone is a metabolism resistant synthetic analog of PGE2. It is a selective agonist for EP3 receptors with a Ki value of 0.35 nM at the human recombinant EP3-??
Sulprostone is a selective agonist of the PGE2 receptor.World Health Organization (WHO)
Sultopride, a neuroleptic indicated for the treatment of acute and chronic psychoses, was introduced on the market in 1976. In the early 1990s, its use was associated with cardiac arrhythmias, some of which were fatal. This led the regulatory authority in France to take restrictive action on the product. Sultopride continues to be marketed in several other countries.Sulprostone ?? ?? ? ???
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Sulprostone ?? ??
???( 68)?? ??
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