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?? 60

?? 60
?? 60 ??? ???
?? ??:
9005-67-8
???:
?? 60
???(??):
???????????????????;????????????????;??60;????????????????(ETHOXYLATEDSORBITANMONOSTEARATE);??????61;??????60;???-3?????????;???-40?????????;???-4?????????;???-60?????????;???-6?????????
???:
Tween 60
???(??):
POLYSORBATE 60;POLYOXYETHYLENE (20) SORBITAN MONOSTEARATE;Tween 60, CP;Polysorbat 60;POLYOXYETHYLENE SORBITAN MONOSTEARATE;T-61;Polyso;FEMA 2916;TWEEN(R) 60;POLYETHYLENE GLYCOL SORBITAN MONOSTEARATE
CBNumber:
CB3315859
???:
C64H126O26
??? ??:
0
MOL ??:
Mol file
MSDS ??:
SDS

?? 60 ??

???
45-50 °C
?? ?
802.68°C (rough estimate)
??
1.044 g/mL at 25 °C(lit.)
???
<10 hPa (20 °C)
FEMA
2916 | POLYSORBATE 60
???
n20/D 1.474
???
>230 °F
?? ??
Store below +30°C.
???
100g/L
?? ?? (pKa)
0[at 20 ℃]
??? ??
powder to lump to clear liquid
??
White or Colorless to Yellow
??
??? ??? ???
??????(pH)
5.5-7.7 (50g/l, H2O, 25℃)
?? ??
??? ???
???
100g/L
???
21.0 to 25.0 ℃
Merck
14,7582
Hydrophilic-Lipophilic Balance (HLB)
15
??? ?? ??
????? - ??
????? - ???
??? ?? ??
Tween 60 (9005-67-8)
InChI
1S/C26H50O10/c1-2-3-4-5-6-7-8-9-10-11-24(30)34-19-18-31-20-22(32-15-12-27)26-25(35-17-14-29)23(21-36-26)33-16-13-28/h22-23,25-29H,2-21H2,1H3
InChIKey
HMFKFHLTUCJZJO-UHFFFAOYSA-N
SMILES
O1C(C(C(C1)OCCO)OCCO)C(OCCO)COCCOC(=O)CCCCCCCCCCC
LogP
3.938 at 25℃
EPA
Polysorbate 60 (9005-67-8)
??
  • ?? ? ?? ??
????? 24/25
WGK ?? 1
RTECS ?? WG2934000
TSCA TSCA listed
HS ?? 34021300
???? ??? 10 - Combustible liquids
?? LD50 orally in Rabbit: > 38000 mg/kg
???? ?? KE-31688
????(GHS):
?? ?:
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
??????:
NFPA 704
1
0 0

?? 60 MSDS


Tween 60

?? 60 C??? ??, ??, ??

????

? (1) ?? : 「???????20」? ???? (1)? ?? ???? ??? ?? ?, ? ?? 2 ????? ??.

??(2) ?? : ? ??? ?????? ?? ??? ?, ? ?? 4.0ppm ????? ??.

??(3) ? : ? ?? 5.0g? ??? ??????? ?? ?????????????? ?? ??? ?, ? ?? 2.0ppm ????? ??.

??(4) ??? : ? ?? 5.0g? ??? ??????? ?? ?????????????? ?? ??? ?, ? ?? 1.0ppm ????? ??.

??(5) ?? : ? ??? ?????? ?? ??? ?, ? ?? 1.0ppm ????? ??.

??(6) 1,4-??? : 「???????20」? ???? (6)? ?? ??? ?, ? ?? 5.0ppm ????? ??.

??(7) ????? : 「???????20」? ???? (7)? ?? ??? ?, 81~96??? ??.

??(8) ??? : 「???????20」? ???? (8)? ?? ??? ?, 44~55??? ??.

??(9) ????? ? ???? : 「???????20」? ???? (9)? ?? ??? ?, ? ?? 21.5~26.0%??? ??. ??? ?? ??? ????? ? ????? ??? ????? ? ?????? ?? ??? ?, 200~212??? ?? ? ???? 52℃????? ??.

????

? (1) ? ??? ???(1→20) 5mL? ???????? 5mL? ??? ??? ??? ?? ?? ?????? ???? ? ? ??? ??.

??(2) ? ?? 60? ? 40 ??? ?? ???? 25℃?? ? ???? ????? ????.

???

? 「???????20」? ???? ?? ????.

??

? ? ??? ??? ?? ???? 1 ?? 2 ??? ? 1M? ?? ??????? ? 20M? ??? ???? ??????? ?????? ?????? ?????? ?????.

?????

? ? ?? 5g? ??? ????????? ?? ??? ?, ? ?? 0.25% ????? ??.

??? ??

Tan paste

??

Tween 60 is an emulsifier manufactured by reacting stearic acid with sorbitol to yield a product which is reacted with ethylene oxide. It is a nonionic, waterdispersible surface-active agent which is very hydrophilic. It is also termed polysorbate 60. It is used in whipped vegetable toppings for overrun and lightness; in cakes for increased volume and fine grain; in icings and confectionery for lightness and syneresis control; and in salad dressing for emulsion stability. It is frequently used with sorbitan monostearate or monoand diglycerides. The typical usage range is 0.10–0.40%.

??

ChEBI: A polymer composed of PEG-ylated sorbitan, where the total number of poly(ethylene glycol) units is 20 (w + x + y + z = 20) and a single terminal is capped by a stearate group.

?? ??

TWEEN 60 is a niosome.

Safety Profile

Moderately toxic by intravenous route. Experimental reproductive effects. Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits acrid smoke and irritating fumes.

?? 60 ?? ?? ? ???

???

?? ??


?? 60 ?? ??

???( 456)?? ??
??? ?? ??? ?? ?? ? ??
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?? 60 ?? ??:

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