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PHENYLGLYOXAL MONOHYDRATE

PHENYLGLYOXAL MONOHYDRATE ??? ???
?? ??:
1075-06-5
???:
PHENYLGLYOXAL MONOHYDRATE
???(??):
PHENYLGLYOXAL;PHENYLGLYOXAL HYDRATE;2,2-Dihydroxy-1-phenylethan-1-one;Ethanone, 2,2-dihydroxy-1-phenyl-;2,2-dihydroxy-acetophenon;2,2-DIHYDROXY-1-PHENYL-ETHANONE;PHENYLGLYOXAL MONOHYDRATE;Phenylglyoxal hydrate 97%;2,2-dihydroxyacetophenone;P-PHENYLGLYOXAL MONOHYDRATE
CBNumber:
CB3454176
???:
C8H8O3
??? ??:
152.15
MOL ??:
1075-06-5.mol
MSDS ??:
SDS

PHENYLGLYOXAL MONOHYDRATE ??

???
76-79 °C(lit.)
?? ?
142 °C125 mm Hg(lit.)
??
1.1603 (rough estimate)
???
1.5120 (estimate)
???
142°C/125mm
?? ??
Sealed in dry,Room Temperature
???
95% ???: ??? 5%, ????? ?? ?? ???, ?? ?? ???
?? ?? (pKa)
10.97±0.41(Predicted)
??? ??
??
??
???? ?? ??? ?? ???? ??
???
?? ????? ??.
BRN
1854721
InChI
1S/C8H6O2.H2O/c9-6-8(10)7-4-2-1-3-5-7;/h1-6H;1H2
InChIKey
YQBLQKZERMAVDO-UHFFFAOYSA-N
SMILES
[H]O[H].[H]C(=O)C(=O)c1ccccc1
CAS ??????
1075-06-5(CAS DataBase Reference)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xn
?? ???? ?? 22-36/37/38
????? 22-26-36
WGK ?? 3
RTECS ?? MD3260000
HS ?? 2914.40.4000
???? ??? 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
?? mouse,LD50,oral,500mg/kg (500mg/kg),Journal of Medicinal and Pharmaceutical Chemistry. Vol. 1, Pg. 365, 1959.
????(GHS): Exclamation Mark (GHS07)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? P264, P270, P301+P312, P330, P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ??
??????:
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
NFPA 704
1
2 0

PHENYLGLYOXAL MONOHYDRATE C??? ??, ??, ??

??

Phenylglyoxal monohydrate was used to modify pig muscle carbonic anhydraseIII and as a specific reagent for arginine groups. It was also used to prepare pyrrolinone and furan derivatives and as as a chemiluminescent reagent for the determination of purines.

Biochem/physiol Actions

Phenylglyoxal is a potent inhibitor of mitochondrial aldehyde dehydrogenase. It reacts with arginine residues in purified Hageman factor (HF, Factor XII) and causes inhibition of its coagulant properties.

PHENYLGLYOXAL MONOHYDRATE ?? ?? ? ???

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PHENYLGLYOXAL MONOHYDRATE ?? ??

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PHENYLGLYOXAL MONOHYDRATE ?? ??:

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